OCT图像运动伪差校正算法的研究  

Study of Motion Artifacts Correction Algorithm in Optical Coherence Tomography Images

作　　者：张明蓉[1] 李跃杰[1,2] 王立伟[1] 高振玉[1] 

机构地区：[1]北京协和医学院中国医学科学院生物医学工程研究所,天津市300192 [2]天津市眼科医学设备技术工程中心,天津市300384

出　　处：《中国医疗器械杂志》2015年第1期5-8,12,共5页Chinese Journal of Medical Instrumentation

基　　金：天津科技创新体系及平台建设计划项目(13ZXGCCX06300);中国医学科学院生物医学工程研究所院所基金(1417)

摘　　要：目的光学相干层析成像系统(Optical Coherence Tomography,OCT)进行动态成像时,运动伪差会使图像产生畸变,从而可能导致临床诊断的误诊以及错诊,运动伪差的校正已经是亟待解决问题。方法首先用改进的自适应非线性复合扩散滤波器对连续采集的序列图像进行预处理降噪,然后用图像的质量重心对畸变的体数据在Y方向进行粗略的对齐,再用差值平均法对Y方向的运动伪差进行校正。结果经过校正,纵切2D图像毛刺消失,表面平滑;3D图像表面平滑,结构清晰,层次分明,视网膜en-face单层切片图像清晰,可以观察到眼底组织细微结构。结论经过运动伪差校正后,眼底视网膜的生理结构得到了真实的反应。Objective Optical coherence tomography images may be distorted by motion artifacts in dynamic imaging, so it may lead to misdiagnosis in clinical diagnosis. Motion artifacts correction has become an urgent issue in optical coherence tomography imaging. Methods Firstly, using the improved complex nonlinear diffusion preprocessing filtering reduced the noise of the sequence images, then using the image mass center aligned the distortion data in the Y direction, finally, using the method of deviation average corrected motion artifacts along the Y direction. Results After correction, the motion artifacts in the longitudinal 2D images and the 3D image disappeared, the surface of the 2D and the 3D image became more smooth, the structure between layers of the images got clear and distinct, retinal en-face single slice image was sharp,and the fundus tissue structure could be observed. Conclusion The algorithm of correction makes the physical structure of the retinal display truly after motion artifacts correction.

关 键 词：光学相干层析成像 运动伪差 校正 

分 类 号：TP391.41[自动化与计算机技术—计算机应用技术]