荆芥止痒丸的质量标准研究  

Research on quality standard of Jingjiezhiyang pills

作　　者：陈杰[1] 仲平[1] 刘长河[2] 

机构地区：[1]河南省食品药品检验所,河南郑州450003 [2]河南省中医药研究院,河南郑州450004

出　　处：《医药论坛杂志》2015年第1期34-37,40,共5页Journal of Medical Forum

摘　　要：目的修订荆芥止痒丸的质量标准。方法采用薄层色谱法(TLC)对荆芥止痒丸中的丹参、赤芍、荆芥、薏苡仁进行定性鉴别;用高效液相色谱法测定其中丹参酚酸B的含量。结果 TLC分离良好,斑点清晰,阴性对照无干扰;丹参酚酸B在13.2μg/ml^52.8μg/ml范围内呈良好的线性关系(r=0.9999),平均加样回收率99.4%,RSD=1.28%(n=6)。结论修订项目可用于荆芥止痒丸的质量控制。Objective To revise the quality standard of Jingjiezhiyang pills. Methods Salviae Mihiorrhizae, Paeoniae Radix Rubra, Sehizonepetae Herba, Coicis Semen were indentified by TLC. The content of Salvianolie acid B was determined by HPLC, Results TLC spots were clear and well - separated without interference from negative sample. The linear ranges was 13.2μg/ml - 1 - 52. 8μg/ml - 1 for Salvianolic acid B （ r = 0. 9999 ） with average recovery of 99.4% （ RSD = 1.28%, n = 6 ）. Conclusion Revised projects is suitable for quality control of jingjiezhiyang pills.

关 键 词：荆芥止痒丸 薄层色谱法 高效液相色谱法 丹参酚酸B 

分 类 号：R284[医药卫生—中药学]