应激性心肌病病理生理机制研究进展  

Current research on pathogenesis of stress cardiomyopathy

作　　者：伍松柏 吕爱莲 

机构地区：[1]长沙市第一医院重症医学科,长沙410005

出　　处：《临床与病理杂志》2015年第2期267-271,共5页Journal of Clinical and Pathological Research

摘　　要：应激性心肌病是一种好发于围绝经期后女性患者,与心理或躯体应激相关,具有短暂性左心室收缩功能障碍特征的获得性心肌病。该病病理生理机制尚未完全阐明,可能的机制主要包括:雌激素缺乏,冠状动脉结构及微血管功能障碍,遗传易患性,儿茶酚胺过负荷等,研究其病理生理学机制有助于应激性心肌病的诊断及治疗方案的选择。Stress cardiomyopathy（SC） occurs more often in postmenopausal women, is characterized by a transient hypokinesis of the left ventricular（LV） apex, and is associated with emotional or physical stress. Its pathophysiology is not clearly understood. It has been suggested that lack of estrogen, coronary structure and microvascular dysfunction, genetic susceptibility and catecholamine overload might contribute to the pathogenesis of SC. The study of pathophysiology related to SC is significant for the understanding of disease diagnosis and treatment options.

关 键 词：应激性心肌病 心尖球囊样综合征 雌激素 冠状动脉 儿茶酚胺 

分 类 号：R542.2[医药卫生—心血管疾病]