香附药材的质量控制方法的探讨  

Investigation on quality control of medicinal material of Cyperi Rhizoma

作　　者：卢君蓉[1] 李文兵 傅超美[1] 季宁平[1] 王世宇[1] 周莉江 刘哿咿 余佳丽[1] 

机构地区：[1]成都中医药大学,四川成都611137 [2]四川新绿色药业科技发展股份有限公司,四川成都611900

出　　处：《中国医院药学杂志》2015年第5期389-392,共4页Chinese Journal of Hospital Pharmacy

基　　金：国家自然科学基金青年基金项目(项目批准号:81303227);成都中医药大学校基金(编号:ZRQN1412)

摘　　要：目的:建立香附药材的质量标准。方法:采用中国药典2010年版一部的方法测定香附药材水分、总灰分、酸不溶性灰分、醇溶性浸出物及挥发油含量;采用薄层色谱法对药材的特征性成分香附烯酮、圆柚酮、α-香附酮进行定性鉴别,运用高效液相色谱法同时测定香附烯酮、圆柚酮、α-香附酮的含量。结果:共得到11个不同产地香附药材水分、总灰分、酸不溶性灰分、醇溶性浸出物及挥发油含量;建立了香附药材中香附烯酮、圆柚酮、α-香附酮的薄层鉴别和含量测定方法。结论:本文建立了较完善的香附药材质量标准,进一步完善了现有标准,可为更好地控制香附质量提供参考。OBJECTIVE To establish quality standards for Cyperi Rhizoma.METHODS The methods described in Chinese Pharmacopoeia（2010 edition）were used to evaluate the content of moisture,total ash,acid insoluble ash,alcohol-soluble extract and volatile oil in Cyperi Rhizoma Thin layer chromatography（TLC）method was used to identify three characteristic ingredients including cyperotundone,nootkatone andα-cyperone in Cyperi Rhizoma,and high performance liquid chromatography（HPLC）method was used to evaluate their contents.RESULTS The contents of moisture,total ash,acid insoluble ash,alcohol-soluble extract and volatile oil were evaluated,and the methods of TLC and HPLC were established to identify and evaluate cyperotundone,nootkatone andα-cyperone in Cyperi Rhizoma from eleven different origins.CONCLUSION A better quality standard is established for Cyperi Rhizoma,which can further improve the current standards and provide a reference for better quality control.

关 键 词：香附 香附烯酮 圆柚酮 Α-香附酮 质量控制 

分 类 号：R932[医药卫生—生药学]