MR磁化率与血肿周围脑水肿的相关性研究  

The correlation study of MR susceptibility and perihematomal brain edema in cerebral hemorrhage

作　　者：陈瑶[1] 田亚楠[1] 李冠武[1] 袁军[1] 常时新[1] 

机构地区：[1]上海中医药大学附属岳阳中西医结合医院影像科,上海200437

出　　处：《放射学实践》2015年第2期124-126,共3页Radiologic Practice

基　　金：上海市科委基础处重点攻关项目(10JC1414600)

摘　　要：目的:探讨MR磁化率与血肿周围水肿(PHBE)间的相关性。方法:52例脑实质内出血的患者分别于发病后第3、10d进行常规MRI及磁量图(QSM)检查。在QSM上计算血肿的平均磁化率,同时在T2FLAIR图上测量PHBE体积,采用Pearson统计分析血肿磁化率与PHBE体积间的相关性。结果:血肿第3d的平均磁化率为(4794.6±420.4)ppm,PHBE体积为(7.49±3.12)mL,两者间存在显著相关性(r=0.974,P<0.001);第10d的平均磁化率为(7388.6±3589.2)ppm,PHBE体积为(11.23±3.79)mL,两者间亦存在显著相关性(r=0.901,P<0.001)。结论:采用MR磁化率计量血肿内铁离子含量对观察PHBE的演变有一定帮助。Objective：To investigate the relationship between MR susceptibility and perihematomal brain edema （PH- BE） in cerebral hemorrhage. Methods： Fifty-two patients who had intracerebral hemorrhage in parenchyma were selected. MRI and quantitative susceptibility mapping （QSM） scan were performed on the 3rd and 10th day after onset. The MR susceptibility of hemorrhage was calculated in QSM, and PHBE was measured in T;-FLAIR imaging. Pearson statistical method was used to analyze the relationship between MR susceptibility and PHBE. Results： The average MR susceptibility of hemorrhage was （4794.6±420.4）ppm and PHBE was （7.49±3.12）mL on the third day. The correlation between them was significant （r= 0. 974, P〈0. 001）. On the 10th day, the average MR susceptibility was （7388.6±3589.2）ppm and PH- BE was （ 11.23 ± 3.79） mL. The correlation was significant （r = 0.901, P〈0. 001）. Conclusion： The release of iron ions from the blood after being dissolved is likely to be an important part in the formation of PHBE. From this point, MR susceptibility measurement of iron content in hematoma is of help is observing PHBE process.

关 键 词：血肿 颅内 脑水肿 磁化率 铁离子 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R742[医药卫生—诊断学]