胰高血糖素瘤综合征1例报告并文献复习  

Glucagonoma syndrome:A report of one case and review of literature

作　　者：周文涛[1] 李初实 匡天涛[1] 楼文晖[1] 王单松[1] 

机构地区：[1]复旦大学附属中山医院普外科,上海200032 [2]浙江省苍南县人民医院,浙江苍南325800

出　　处：《中国实用外科杂志》2015年第3期313-315,共3页Chinese Journal of Practical Surgery

摘　　要：目的探讨胰高血糖素瘤的临床特征及诊治要点。方法回顾性分析复旦大学附属中山医院2014-07-01收治的1例胰高血糖素瘤病人资料,并结合文献复习。结果该病人有典型的溶解游走性坏死性红斑、糖尿病、贫血及消瘦等胰高血糖素瘤综合征表现,曾多次误诊为皮炎。腹部CT示胰体尾占位性病变。经胰体尾联合脾脏切除术治疗后,血糖恢复正常,症状体征明显改善。结论胰高血糖素瘤临床表现复杂,易误诊,影像学检查对诊断有一定帮助,手术切除是其有效的治疗方法。Objective To investigate the clinical features,diagnosis and treatments of glucagonoma.MethodsTheclinical data of one patient with glucagnoma admitted in Zhongshan Hospital of Fudan University was analyzedretrospectively.ResultsThe patient had been misdiagnosed as dermatitis for many times. Although the patient got thetypical symptoms of glucagonoma syndrome such as necrolytic migratory erythema,diabetes mellitus,anemia,weight lossand so on. Abdominal CT scan showed a tumor mass in pancreatic body and tail. After surgical removal of the tumor,thepatient＇s glucose level and systemic features resolved.ConclusionGlucagonoma is very easy to get misdiagnosisbecause of its multiple clinical manifestations. Imaging examination is helpful for the diagnosis and surgical resection isstill an effective method.

关 键 词：胰高血糖素瘤综合征 溶解坏死性游走性红斑 糖尿病 

分 类 号：R6[医药卫生—外科学]