原发性高血压患者尿微量白蛋白与中医证型的相关性研究  

Correlation of Urinary Microalbumin and Carotid Atherosclerosis with TCM Syndromes in Patients with Essential Hypertension

作　　者：徐立思[1] 符徳玉 桂明泰[2] 徐邦杰[2] 

机构地区：[1]上海市中医文献馆,上海200020 [2]上海中医药大学附属岳阳中西医结合医院,上海200437

出　　处：《中华中医药学刊》2015年第3期564-566,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：国家"十一五"科技支撑计划项目分课题(2006BAI01A03)

摘　　要：目的:初步探讨原发性高血压(EH)患者尿微量白蛋白(MA)水平及颈动脉硬化与中医证型的相关性。方法:通过对337例EH患者尿MA水平及颈动脉超声、心超的检测,同步测量血压、身高、体质量,采集相关病史,结合四诊情况进行中医辨证,进行相关数据的统计分析。结果:4种常见中医证型尿MA的阳性率以痰湿壅盛(33.3%)、阴阳两虚(46.7%)显著增高,阴阳两虚与痰湿壅盛证的颈动脉硬化及左室肥厚的发生率高于肝火亢盛与阴虚阳亢证(P<0.05)。结论:EH患者阴阳两虚证和痰湿壅盛证尿MA水平更高,可能更易发生颈动脉硬化及心、脑靶器官损害。Objective： To study the correlation of urinary MA and carotid atherosclerosis with TCM syndromes in patients with essential hypertension. Methods： Urinary MA and carotid ultrasound were detected and BP,body height and weight were measured synchronously. Medical history was required in detail（ including cardiovascular risk factors and target organ damages）. TCM syndrome was differentiated by the four diagnostics. And then we analyzed the data by using correlation,regression test and so on. Results： The positive rate of MA in different TCM syndromes： stagnation of phlegm-dampness type（ 33. 3%） and yin- yang deficiency type（ 46. 7%） rised significantly. These two TCM syndromes were prone to cause carotid atherosclerosis and left ventricular hypertrophy. Conclusion： The level of MA is higher in stagnation of phlegm- dampness type and yin- yang deficiency type and these two TCM syndromes are prone to cause carotid atherosclerosis and left ventricular hypertrophy.

关 键 词：原发性高血压 尿微量白蛋白 中医证型 

分 类 号：R544.1[医药卫生—心血管疾病]