头孢哌酮钠舒巴坦钠联合左氧氟沙星治疗呼吸道重症感染疾病的临床疗效  

The Tlinical Efficacy of Cefoperazone Sodium and Sulbactam Sodium for in Jection Combined with Levofloxacin in the Treatment of Respiratory Diseases and Severe Infection

作　　者：杨茵梅[1] 

机构地区：[1]广东省高州市人民医院,广东茂名525200

出　　处：《中国药物经济学》2015年第2期33-35,共3页China Journal of Pharmaceutical Economics

摘　　要：目的探讨头孢哌酮钠舒巴坦钠联合左氧氟沙星治疗呼吸道重症感染疾病的临床疗效。方法选取在我院就诊的呼吸道重症感染疾病患者88例,随机分为对照组和治疗组,每组44例。对照组患者采用头孢哌酮钠舒巴坦钠治疗;治疗组患者采用头孢哌酮钠舒巴坦钠联合左氧氟沙星治疗。比较两组患者疗效。结果治疗组患者总有效率为90.9%,明显优于对照组的70.5%;两组患者治疗后血气分数改善幅度明显优于治疗前,且治疗组患者治疗后血气分数改善幅度明显优于对照组;治疗组患者呼吸道重症感染细菌检查结果转阴时间、症状消失时间、治疗总时间明显短于对照组;对照组患者治疗期间有2例出现不良反应,治疗组有7例患者出现不良反应;差异均有统计学意义(均P<0.05)。结论头孢哌酮钠舒巴坦钠联合左氧氟沙星治疗呼吸道重症感染疾病临床疗效明显,且安全性高。Objective To clinical efficacy of cefoperazone sodium and Sulbactam Sodium for injection combined with levofloxacin in the treatment of respiratory diseases and severe infection.Methods Select 88 cases of respiratory tract infection in patients with severe disease in our hospital,were randomly divided into control group and treatment group,44 cases in each group.The control group was treated with cefoperazone sodium and Sulbactam Sodium for treatment;the treatment group was treated with cefoperazone sodium and Sulbactam Sodium for injection combined with levofloxacin in the treatment of.Compare two groups of curative effect.Results The patients in the treatment group the total effective rate was 90.9%,significantly better than the control group 70.5%;the amplitude is obviously better than that of treatment to improve blood gas fraction of two groups of patients after treatment and before,the patients in the treatment group were improved after treatment was significantly better than the control group;the treatment group patients with respiratory tract infection results severe bacterial examination time for negative,symptoms disappeared time,total treatment time was significantly shorter than the control group;control group patients treated during 2 cases of adverse reactions,treatment group of 7 cases of patients with adverse reactions,the difference had statistical significance（P〈0.05）.Conclusion Cefoperazone sodium and Sulbactam Sodium for injection combined with levofloxacin in the treatment of severe respiratory infection disease clinical curative effect is obvious,and the safety is high.

关 键 词：左氧氟沙星 头孢哌酮钠舒巴坦钠 呼吸道重症感染 安全性 

分 类 号：R562[医药卫生—呼吸系统]