冠状动脉慢血流患者肺功能的变化  

Change of pulmonary function in patients with slow coronary flow

作　　者：杨硕[1] 贺立群[2] 雷健[2] 罗光伟[1] 胡小萍[1] 聂红[1] 李佐民[2] 昌薇[2] 柯于鹤[2] 

机构地区：[1]湖北省武汉市第一医院呼吸内科,430022 [2]湖北省武汉市第一医院心血管内科,430022

出　　处：《安徽医学》2015年第2期157-159,共3页Anhui Medical Journal

基　　金：武汉市卫生局资助课题(项目编号:2010WX10C05)

摘　　要：目的了解冠状动脉慢血流(SCF)现象患者肺功能变化。方法 60例在我院进行冠状动脉造影检查未发现明显冠状动脉狭窄的患者,根据TIMI血流帧数分为SCF组(30例)以及冠状动脉正常血流组(NCF组,30例),对两组患者的临床特点、肺功能水平及基础呼吸困难指数进行比较分析。结果与NCF组比较,SCF组患者一秒用力呼气溶积(FEV1)有下降但差异无统计学意义(P>0.05),FEV1%预计值、FEV1/FVC、MVV、MVV%预计值、基础呼吸困难指数明显下降,而hs-CRP水平、肺功能受损明显增加(P<0.05)。结论 SCF患者肺功能下降,可能与全身炎症反应相关。Objective To investigate the change of pulmonary function in patients with slow coronary flow (SCF).Methods 60 patients without significant coronary artery stenosis confirmed by inspection of coronary angiography in our hospital,were divided into two groups according to TIMI frame count:slow coronary flow group (group SCF,30 patients)and normal coronary flow group (group NCF,30 patients).The clinical features,pulmonary function,and baseline dyspnoea index (BDI)between the two groups were compared.Results Compared with group NCF,the patients in group SCF had lower FEV1 value,but the difference between groups appeared to be statistically nonsignificant (P>0.05).Results of FEV1%predicted value,FEV1/FVC,MVV,MVV%predicted value,and BDI in group SCF reduced significantly,together with higher serum hs-CRP level,which brought out pulmonary insufficiency (P<0.05 ).Conclusion The pulmonary function in patients with slow coronary flow decreased moderately,which might be in relation to systemic inflammatory response.

关 键 词：冠状动脉慢血流 肺功能 高敏C反应蛋白 

分 类 号：R543.3[医药卫生—心血管疾病]