广州市荔湾区美沙酮维持治疗者HIV、HCV和梅毒感染状况的调查研究  

Investigation and analysis of infection of HIV,HCV and syphilis among patients with methadone maintenance treatment in Liwan district of Guangzhou

作　　者：张秋丽[1] 付丽[1] 陈若恒[1] 谭志熹[1] 

机构地区：[1]广州市荔湾区疾病预防控制中心,广东广州510176

出　　处：《中国卫生检验杂志》2015年第4期581-583,601,共4页Chinese Journal of Health Laboratory Technology

摘　　要：目的分析广州市荔湾区接受美沙酮维持治疗者HIV、HCV和梅毒感染状况,为采取针对性干预措施提供依据。方法收集广州市荔湾区2012年-2013年接受美沙酮维持治疗的282名吸毒者的资料,对照他们的HIV、HCV和梅毒感染状况,分析他们的人群特征以及感染差异。结果广州市荔湾区美沙酮维持治疗者中HIV感染率为4.3%、HCV感染率为95.1%、梅毒感染率为7.1%。注射吸毒者和有注射吸毒史者HCV感染率明显高于口吸或烫吸者和无注射吸毒史者;女性的HIV和梅毒感染率明显高于男性;服务业人群梅毒感染率明显高于其他职业人群。结论广州市荔湾区吸毒人群HIV、HCV和梅毒感染率较高,注射吸毒和不安全性行为是感染的主要因素,对该人群应加强HIV、HCV和梅毒筛查检测,积极开展健康教育和行为干预。Objective To analyze the infection of human immunodeficiency virus（ HIV）,hepatitis C virus（ HCV） and syphilis among patients with methadone maintenance treatment（ MMT） in Liwan district of Guangzhou in order to provide scientific basis for targeted intervention measures. Methods Information of 282 drug users who received MMT in Liwan district from 2012 to2013 was collected,and epidemiological feature and infective difference of these groups were analyzed according to the comparison of HIV,HCV and syphilis infections. Results The infection rates of HIV,HCV and syphilis of MMT cases in this study was respectively 4. 3%,95. 1% and 7. 1%. The HCV infection rate in the groups using drug- injecting method and having history of drug- injecting was significant higher than those adopting oral- taking or snorting method and without history of drug-injecting. Compared with males,females had an obvious higher infection of HIV and syphilis. Syphilis infection rate of service industry was significantly higher than that of other occupations. Conclusion The infection rates of HIV,HCV and syphilis of drug users in Liwan district was very high. The most important factors of infection are injection drug use and unsafe sex. The screening tests of the three items of these groups should be strengthened and more effective health education and behavior intervention should be carried out.

关 键 词：美沙酮 艾滋病病毒 丙型肝炎病毒 梅毒 感染 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]