靶控输注枸橼酸芬太尼或瑞芬太尼用于妇科腹腔镜手术麻醉的临床研究  

Clinical studies on target-controlled infusion of fentanyl citrate or remifentanil anesthesia for laparoscopic surgery in gynecology

作　　者：梅菊香[1] 周泉华[1] 尹永胜[1] 徐向杨[1] 吴范[1] 赵娟[1] 

机构地区：[1]江苏省启东市人民医院,江苏启东226200

出　　处：《中国医药科学》2015年第2期82-83,86,共3页China Medicine And Pharmacy

摘　　要：目的探讨和分析在妇科腹腔镜手术麻醉中应用靶控输注枸橼酸芬太尼或瑞芬太尼的临床疗效及价值。方法选取2013年2-12月在我院接受妇科腹腔镜手术治疗的患者90例为研究对象,随机分成A组和B组,A组采取异丙酚复合靶浓度1.5ng/m L枸橼酸芬太尼进行手术麻醉,B组采取异丙酚复合靶浓度4.0ng/m L瑞芬太尼进行手术麻醉,其中异丙酚靶浓度均为3ug/m L;观察和对比两组SBP（收缩压）、SDP（舒张压）和HR（心率）的变化等情况。结果麻醉后,B组的SBP（收缩压）、SDP（舒张压）和HR（心率）的变化等情况显著好于A组,差异有统计学意义（P〈0.05）。结论在妇科腹腔镜手术中应用靶控输注枸橼酸芬太尼进行麻醉,其血流动力学更加稳定,但苏醒时间会慢于瑞芬太尼,瑞芬太尼麻醉后给予镇痛时间会提前,临床医师需注意。Objective To investigate and analysis the clinical effects and value of target-controlled infusion of fentanyl citrate or remifentanil application in gynecological laparoscopic surgery. Methods Selected 90 patients after laparoscopic surgical treatment in our hospital as the object of study, and randomly divided them into group A and group B, group A took composite target propofol concentration 1.5ng/m L citrate fentanyl on anesthesia, group B take composite target propofol concentration 4.0ng/m L remifentanil on anesthesia, target concentration of two groups propofol were 3ug/m L; Observed and compared the changes on SBP（systolic pressure）, the SDP（diastolic pressure） and so on of two groups. Results After anesthesia, SBP（systolic blood pressure）, SDP（DBP） and HR（heart rate） changes of B group were significantly better than A group, with statistical difference（P〈0.05）. Conclusion The application of fentanyl citrate target controlled infusion in gynecological laparoscopic surgery anesthesia, has more stable hemodynamics, however awakening time is slower than remifentanil, remifentanil will give analgesic time after anesthesia ahead of time, which clinicians should pay attention to.

关 键 词：腹腔镜手术 靶控输注 枸橼酸芬太尼 瑞芬太尼 麻醉 

分 类 号：R614.24[医药卫生—麻醉学]