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机构地区:[1]昆明市经开人民医院外科,云南昆明650217 [2]昆明医科大学第二附属医院泌尿外科二病区,云南昆明650101
出 处:《昆明医科大学学报》2015年第3期91-94,共4页Journal of Kunming Medical University
基 金:云南省科技厅应用基础研究基金资助项目(2011FZ125)
摘 要:目的观察双石通淋胶囊治疗慢性细菌性前列腺炎的临床疗效.方法采用随机分组平行对照单盲观测的临床试验研究方法.将60例门诊确诊为慢性细菌性前列腺炎(NIH-CPSI评分≥14分,EPS-WBC≥10个/高倍视野、培养有致病菌生长)的患者,随机分为治疗组(双石通淋胶囊)和对照组(前列康片),每组30例,连续用药6周.治疗前后分别观察NIH-CPSI、EPS.采用美国国立卫生研究院(NIH)制定的前列腺炎症状评分(CPSI)标准及前列腺液白细胞(EPS-WBC)数值判定疗效.结果治疗组总有效率为83.3%、对照组为43.3%(P<0.05).治疗前NIH-CPSI总评分:治疗组为(24.40±5.04)分、对照组为(23.80±5.34)分;治疗后NIH-CPSI总评分:治疗组(9.93±8.04)分、对照组为(16.83±9.27)分;2组比较P<0.05.NIH-CPSI疼痛症状评分,治疗前治疗组为(13.86±1.52)分、对照组为(13.53±1.25);治疗后治疗组为(5.40±2.73)分、对照组为(9.83±3.45)分,2组比较P<0.05.结论双石通淋胶囊治疗慢性细菌性前列腺炎疗效较好.Objective To observe the efficacy of Shuangshi Tonglin Capsule in treating chronic bacterial prostatitis. Methods The randomized parallel,controlled and single blind clinical trial was adopted. Sixty patients were diagnosed as chronic bacterial prostatitis with National Institutes of Healthy Chronic Prostatitis Symptom Index(NIH-CPSI) was ≥14,white blood cells was ≥10/HP in examination prostatic secretion(EPS),and culture of pathogenic bacteria was positive in EPS. We randomly divided the 60 patients into two groups:treatment group and control group,30 patients in each group. Patients in the treatment groment were treated with Shuangshi Tonglin Capsule and patients in the control group were given Qianliekang Tablets. The NIH-CPSI and EPS were observed before and after a 6-week treatment. The efficacy was evaluated by the NIH Chronic Prostatitis Symptom Index(CPSI) and examination prostatic secretion(EPS). Results The total clinical effectiveness was 83.3% in the treatment group and 43.3% in the control group(P〈0.05). Before and after treatment,the total NIH-CPSI score in the treatment group was(24.40±5.04) and(9.93±8.04), in the control group was(23.80±5.34) and(16.83±9.27)(P〈0.05). Before and after treatment NIH-CPSI pain score was(13.86±1.52) and(5.40±2.73) in the treatment group,(13.53±1.25) and(9.83±3.45)(P〈0.05) in the control group. Conclusion Shuangshi Tonglin Capsule has good effect in the treatment of chronic bacterial prostatitis.
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