冷冻联合5-氨基酮戊酸光动力治疗尖锐湿疣的临床疗效观察和护理体会  

Efficacies of cryotherapy plus 5-aminolevulinic acid-photodynamic therapy in patients with condyloma acuminatum and nursing experiences

作　　者：段颖[1] 黄英[1] 

机构地区：[1]首都医科大学宣武医院皮肤科,北京100053

出　　处：《中华全科医师杂志》2015年第3期230-232,共3页Chinese Journal of General Practitioners

摘　　要：用冷冻联合5-氨基酮戊酸光动力（ALA—PDT）和单独光动力两种方法治疗65例尖锐湿疣患者。冷冻时动作轻柔，深度适中，光动力治疗时敷药、照光护理细致、全面，出现不良反应者给予康复新液湿敷和抗生素软膏。联合组先冷冻2次，再经ALA—PDT治疗1～3次，单独治疗组经ALA—PDT治疗1～4次，所有患者均给予1次ALA—PDT巩固治疗。联合组治愈率83％（29／35），复发率17％（6／35）；光动力组治愈率70％（21／30），复发率30％（9／30）。冷冻联合光动力疗法是一种实用、疗效更好、复发率更低的治疗方法，治疗时全面、细致、舒适的护理能保证临床疗效，减少复发和治疗的不适感。A total of 65 patients of condyloma acuminatum （CA） received cryotherapy plus 5- aminolevulinic acid-photodynamic therapy （ALA-PDT） or ALA-PDT alone. During cryotherapy, handling was gentle with a moderate depth. The nursing of PDT was both meticulous and comprehensive. Patients with adverse reactions received Kangfuxin liquid for wet packing and topical antibiotic ointment. The combination group received cryotherapy for 2 sessions and then PDT for 1 - 3 sessions while PDT was administered for 1 -4 sessions in single PDT group. Then all patients received PDT once for consolidation therapy. For groups 1 and 2, the effective rates were 83% and 70% and the recurrent rates 17% and 30% respectively. Cryotherapy plus ALA-PDT is feasible for CA and it offers better efficacies and lower recurrent rates. And comprehensive, meticulous and comfortable nursing may achieve clinical efficacies, reduce the recurrent rate and minimize discomforts during treatment.

关 键 词：光化学疗法 5-氨基酮戊酸 护理 

分 类 号：R752.53[医药卫生—皮肤病学与性病学]