抑肝扶脾清热利湿法治疗广东地区腹泻型肠易激综合征卫生经济学评价  

Evaluation of health economics of method of supporting spleen,restricting liver,clearing heat,and promoting diuresis in treatment of diarrhea- predominant irritable bowel syndrome in Guangdong,China

作　　者：彭少林[1] 常东 汪栋材[1] 张文妍[1] 

机构地区：[1]广东省深圳市中医院,广东深圳518033 [2]武警广东边防总队医院,广东深圳518029

出　　处：《湖南中医杂志》2015年第2期11-13,共3页Hunan Journal of Traditional Chinese Medicine

基　　金：广东省中医药管理局资助项目(编号:20132023)

摘　　要：目的:对分别用中药与西药治疗腹泻型肠易激综合征(IBS-D)进行临床疗效及卫生经济学评价与比较。方法:将120例IBS-D纳入病例分为中药组和西药组各60例,中药组采用抑肝扶脾清热利湿法治疗,西药组口服马来酸曲美布丁片和枯草杆菌二联活菌肠溶胶囊治疗。按照IBS病情变化积分表(BSS)评分系统,观察并评价治疗后两组临床疗效;治疗结束后的第3个月随访,比较分析两组患者治疗期间及治疗后的直接成本、间接成本、随访复发率及其随访成本等。结果:总有效率中药组为91.37%,西药组为77.19%,两组比较,差异有统计学意义(P<0.05);治疗结束后的第3个月随访,复发率中药组为44.83%,西药组为64.91%,两组比较,差异有统计学意义(P<0.05);且中药组治疗期间直接成本、总成本均低于西药组,中药组的直接成本-效果比、总成本-效果比及随访未复发率与成本-效果比都明显低于西药组。结论:中药治疗IBS-D疗效肯定,且有较好的成本-效果比。Objective： To investigate the clinical efficacy of traditional Chinese medicine（ TCM） and Western medicine in the treatment of diarrhea- predominant irritable bowel syndrome（ IBS- D） and to evaluate their health economics. Methods： A total of 120 included cases of IBS- D were divided into TCM group（ n = 60） and Western medicine group（ n = 60）. The TCM group was treated with the method of supporting spleen,restricting liver,clearing heat,and promoting diuresis,and the Western method group was treated with trimebutine maleate tablets and live combined Bacillus subtilis and Enterococcus faecium enteric- coated capsules. The clinical efficacy of the two groups was observed and evaluated according to bowel scoring system（ BSS）. The two groups were followed up in the third month after treatment,and the direct cost and indirect cost during treatment and after treatment,recurrence rate during follow- up,and the follow- up cost of the two groups were compared and analyzed. Results： The overall response rates of the TCM group and Western medicine group were 91. 37% and 77. 19%,respectively,and the difference was significant（ P〈0. 05）. During the follow- up in the third month after treatment,the recurrence rates of the TCM group and Western medicine group were 44. 83% and 64. 91%,respectively,and the difference was significant（ P〈0. 05）. Compared with the Western medicine group,the TCM group had lower direct cost and total cost,and also had significantly lower direct cost / effectiveness ratio,total cost / effectiveness ratio,recurrence rate during follow- up,and cost / effectiveness ratio. Conclusion： TCM shows satisfactory clinical efficacy in the treatment of IBS- D and has a good cost / effectiveness ratio.

关 键 词：肠易激综合征 腹泻型 抑肝扶脾清热利湿法 卫生经济学 成本 

分 类 号：R259.744[医药卫生—中西医结合]