橙皮苷及橙皮素清除超氧阴离子自由基能力的研究  

Scavenging Activity of Superoxide Free Radical of Hesperidin and Hesperetin

作　　者：许树军[1] 朱琪[1] 于子惠[1] 徐暘[1] 邹淑君[1] 

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040

出　　处：《中医药学报》2015年第1期56-58,共3页Acta Chinese Medicine and Pharmacology

基　　金：黑龙江省教育厅资助项目(No.12531648);黑龙江中医药大学校基金科研课题(201103)

摘　　要：目的:比较橙皮苷和橙皮素清除超氧阴离子自由基(O-2·)的活性。方法:邻苯三酚自氧化法测定橙皮苷和橙皮素对O-2·的清除作用。结果:橙皮苷和橙皮素对O-2有一定的清除作用,在实验范围内,清除效果随浓度的增大而增大。橙皮素清除O-2·的能力明显强于橙皮苷。结论:橙皮素比橙皮苷体外抗氧化能力强。Objective： To compare the scavenging ability of superoxide free radical（ O2^-·） of hesperidin and hesperetin.Methods： The scavenging reaction to O2^-· of hesperidin and hesperetin was studied by the autoxidation of pyrogallol system. Results： Hesperidin and hesperetin were able to scavenge the O2^-·,and the scavenying capacity showed a concentration- dependent manner. The scavenying activity of O2^-· of hesperetin was significantly stronger than that of hesperidin. Conclusion： The antioxidant activity in vitro of hesperetin is stronger than that of hesperidin.

关 键 词：橙皮苷 橙皮素 O2^-· 

分 类 号：R284.1[医药卫生—中药学]