核离子计数检测器在药物分析中的应用  

Advances on the application of nano quantity analyte dectecor in pharmaceutical analysis

作　　者：樊玉丹 李银峰[2] 陈晓雨[1] 黄凤芸 林秀云[1] 靳朝东[2] 

机构地区：[1]天津中医药大学,天津300193 [2]天津药物研究院分析测试中心,天津300193

出　　处：《现代药物与临床》2015年第2期228-232,共5页Drugs & Clinic

摘　　要：核离子计数检测器(NQAD)是一种新型的通用型高效检测器,基于水凝粒子计数专利技术和气溶胶原理,操作简单,具有较高的信噪比和灵敏度,检测范围广,重复性和稳定性好,可以检测到纳克级水平。该检测器适用于几乎所有物质(挥发性物质除外),检测药物一般不需要衍生化处理,准确度较高。介绍其在抗生素类、糖类、离子类、酸类、聚合物类、皂苷类、甾醇类、脂类和环胺类等化合物分析中的应用。Nano quantity analyte dectecor（NQAD） is a new general detector, which is based on the patented technology of water condensation particle counting and aerosol principle. Therefore, some advantages can be achieved such as simple and reliable operation, high signal-to-noise ratio and sensitivity, wide range of detection, excellent precision and stability, and the detection of ng level. The detector is suitable for almost all substances except volatile ones, which does not need derivative processing and has high degree of accuracy. The application of nano quantity analyte detector in analysis of antibiotics, sugar, ions, acids, polymers, saponins, lipids, sterols, and heterocyclic amines are introduced.

关 键 词：核离子计数检测器 水凝粒子计数器 高效液相色谱 药物分析 

分 类 号：R917[医药卫生—药物分析学]