七氟烷吸入麻醉与丙泊酚全凭静脉麻醉在食管胃底静脉曲张内镜治疗术中的麻醉效果比较  

Comparison of anesthetic effect of sevoflurane inhalation general anesthesia with propofol intravenous anesthesia during endoscopic esophageal gastric variceal therapy

作　　者：唐玲华[1] 陈小亮[2] 夏中元[1] 孟庆涛[1] 

机构地区：[1]武汉大学人民医院麻醉科,湖北武汉430060 [2]武汉市儿童医院小儿骨科,湖北武汉430015

出　　处：《实用医院临床杂志》2015年第2期90-93,共4页Practical Journal of Clinical Medicine

摘　　要：目的比较七氟烷吸入全身麻醉与丙泊酚全凭静脉麻醉在食管胃底静脉曲张内镜治疗术中的麻醉效果和安全性。方法 82例行食管胃底静脉曲张套扎和硬化治疗术患者,按随机数字表法分为S组及P组各41例,分别给予七氟烷吸入全身麻醉及丙泊酚静脉全身麻醉。比较两组患者生命体征及麻黄碱使用情况、术后苏醒时间、拔管时间及术后不良反应。结果两组患者插管后10、15、20 min平均动脉压及插管后5 min心率差异均有统计学意义(P<0.05)。S组患者苏醒时间、拔管时间及使用麻黄碱患者均较P组少,Ramsay镇静评分高于P组,差异均有统计学意义(P<0.05)。麻醉医生及患者对麻醉质量评分两组差异有统计学意义(P<0.05)。结论与丙泊酚静脉麻醉相比,七氟烷吸入全身麻醉用于食管胃底静脉曲张内镜治疗术患者,血流动力学更平稳,患者术后苏醒迅速,苏醒质量高,不良反应少,有更好的临床应用价值。Objective To compare the safety and anesthetic efficacy of sevoflurane inhalation general anesthesia with propofol intravenous anesthesia during endoscopic variceal ligation or endoscopic variceal sclerotherapy. Methods Eighty-two patients undergoing endoscopic variceal ligation or endoscopic variceal sclerotherapy were randomly divided into sevoflurane group（ group S） and propofol group（ group P）,41 in each group. The patients received general anesthesia by sevoflurane inhalation and intravenous propofol,respectively. Vital signs,usage of ephedrine,time of postanaesthetic recovery and extubation,as well as postoperative adverse reactions were compared between the two groups. Results There was a significant difference in the mean artery pressure at 10,15 and 20 min and heart rate at 5 min after intubation between the two groups（ P〈0. 05）. The time of postanaesthetic recovery and extubation and the usage of ephedrine in the group S were less than that in the group P（ P〈0. 05）. The Ramsay score in the group S was higher than that in the group P（ P〈0. 05）. There was significantly different between the two groups in the anesthesia quality score evaluated by anesthetists and patients（ P〈0. 05）. Conclusion Compared to propofol intravenous anesthesia,sevoflurane inhalation general anesthesia shows more stable hemodynamics,faster postanaesthetic recovery and higher quality anesthesia recovery. Thus,it has a better clinical application values.

关 键 词：静脉全身麻醉 吸入全身麻醉 食管静脉曲张 套扎治疗术 硬化治疗术 

分 类 号：R614.2[医药卫生—麻醉学]