544例药品不良反应报告分析  

ADR Reports: Analysis on 544 Cases

作　　者：王娜[1,2] 杨悦[1] 

机构地区：[1]沈阳药科大学工商管理学院,沈阳110016 [2]辽宁省人民医院药学部,沈阳110016

出　　处：《中国医院用药评价与分析》2015年第2期254-257,共4页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:了解辽宁省人民医院(以下简称"我院")药品不良反应(ADR)发生的特点及规律,为临床合理用药提供参考,以期进一步提高我院ADR监测工作水平。方法:对2006年1月—2014年1月我院上报的544例有效ADR报告进行回顾性分析。结果:我院ADR共涉及222种药品(588例次),以抗微生物药为主(226例次,占总例次数的38.4%);剂型以注射剂型为主(474例次,占总例次数的80.6%);累及系统以皮肤及附件损害最为突出。结论:临床医护人员需重视ADR的监测和上报,注意抗微生物药、中药注射剂和复方制剂的合理使用,减少和防止ADR的重复发生。OBJECTIVE：To analyze the characteristics and regularities of the adverse drug reactions （ADRs）in Liaoning Provincial People＇s Hospital （ hereinafter referred to as ＂our hospital＂ ） so as to provide reference for clinical rational use of drugs and improvement of ADR monitoring reported by our hospital from Jan. 2006 to Jan. 2014 were in our hospital. METHODS： A total of 544 analyzed retrospectively. RESULTS： A total ADR cases of 222 drugs （588 episodes）were involved in the 544 ADR cases, predominantly the antimicrobial drugs with 226 episodes, accounting for 38.4% of total and injections （474 episodes, 80. 6% ）. Multiple organs and （or） systems were involved, with the lesion of skin and its appendages topping the list. CONCLUSIONS： Physicians and nurses should give close attention to ADR monitoring and reporting and rational use of antimicrobial drugs, traditional Chinese medicine injections and compound preparations in order to reduce and prevent the reoccurrence of ADR.

关 键 词：药品不良反应 合理用药 药学监护 

分 类 号：R969.3[医药卫生—药理学]