甲基橙合成方法的研究  

Study on synthesis method of methyl orange

作　　者：黄飞[1] 屈飞强 任晓琼[1] 李建华[1] 吴文芳[1] 

机构地区：[1]黄山学院化学化工学院,安徽黄山245041

出　　处：《齐齐哈尔大学学报（自然科学版）》2015年第2期30-34,共5页Journal of Qiqihar University(Natural Science Edition)

基　　金：国家级大学生创新创业训练计划项目(201410375003);安徽省大学生创新创业训练计划项目(AH201310375027);黄山学院自然科学研究项目(2012xkj006)

摘　　要：以对氨基苯磺酸、亚硝酸钠和N,N-二甲基苯胺为原料,通过重氮化反应和偶合反应合成了甲基橙,比较了传统法、绿色化法和微量法合成甲基橙的三种方法。考察了反应物用量、反应温度、反应时间、溶液p H值和辅助剂对合成甲基橙的影响,得到了优化合成条件。实验结果表明,微量法合成甲基橙反应过程时间短、产率高,产品纯度好;其中N,N-二甲苯胺用量为0.13m L,反应温度为0~5℃,反应时间为3h,溶液p H值为6,辅助剂为乙醇或乙醚,在此条件下,甲基橙的最高产率可达82.01%。该方法操作简单,原料消耗少,生产成本低,环境污染小,产品产率高。The p-aminobenzene sulfonic acid, N,N-dimethylaniline, sodium nitrite as raw material, methyl orange was synthesized by diazotization and coupling reaction. The traditional method, green and micro method of synthesis methyl orange were compared. The dosage of the reactant, reaction temperature, reaction time, pH value of the solution and the adjuvant effect were studied. The experimental results show that the reaction time of micro method of synthesis methyl orange was shortest, the yield was higher, and the product quality was better. The dosage of N,Ndimethylaniline was 0.13 mL, the reaction temperature was 0-5℃, the reaction time was 3 h, pH value of the solution was 6, the adjuvant was ethanol or ether, the methyl orange yield was up to 82.01%. The method is easily operate, the raw material and cost of production are reduced, environmental pollution is little, and the production is high too.

关 键 词：对氨基苯磺酸 甲基橙 重氮化反应 偶合反应 合成 

分 类 号：O625.64[理学—有机化学]