刺五加浸膏化学成分研究  

Study on the chemical constituents of the extract of Acanthopanax senticosus

作　　者：李慧慧[1] 马淑丽[1] 栗娜[1] 张文治[1] 

机构地区：[1]齐齐哈尔大学化学与化学工程学院,黑龙江齐齐哈尔161006

出　　处：《齐齐哈尔大学学报（自然科学版）》2015年第2期48-49,共2页Journal of Qiqihar University(Natural Science Edition)

基　　金：黑龙江省教育厅科学技术研究项目(11551532)

摘　　要：研究药用刺五加浸膏的化学成分。采用硅胶柱色谱、HPLC色谱等方法分离纯化,对刺五加浸膏进行化学成分的分离,根据理化性质和波谱数据进行结构鉴定。从刺五加浸膏中分离并鉴定了5个化合物,分别为3-甲氧基-4-羟基反式苯丙烯酸正十八醇酯(1),2-呋喃甲酸(2),反式对羟基肉桂酸(3),异嗪皮啶(4),异香草酸(5)。化合物1,2,3,5为首次从刺五加浸膏中分离得到。To study the chemical constituents from the extract of Acanthopanax senticosus. Chemical constituents were isolated by column chromatography and semi-prepared HPLC, isolation of the chemical constituents of Acanthopanax senticosus extract the structures were elucidated spectral data and physical-chemical properties. Five compounds were isolated and respectively identified as Octadecanyl-3-methoxy-4-hydroxy-benzeneacrylate （1）, 2-Furancarboxylic acid （2）, E-p-hydroxy-cinnamic acid （3）, isofraxidin （4）, Isovanillic acid （5） ~ Compound 1, 2, 3, 5 are isolated from the extract of Acanthopanax senticosus for the first time.

关 键 词：刺五加浸膏 化学成分 

分 类 号：R286.0[医药卫生—中药学]