我院2010年10月-2013年10月非甾体抗炎药在外科术后的应用分析  

Analysis of the Utilization of Non-steroidal Anti-inflammatory Drugs in Our Hospital after Surgery from Oct.2010 to Oct. 2013

作　　者：骆松梅[1] 蒋晓梅[1] 吕碧华[1] 龚津津 

机构地区：[1]丽水市中心医院药学部,浙江丽水323000 [2]温州医科大学药学院,浙江温州325035

出　　处：《中国药房》2015年第8期1033-1036,共4页China Pharmacy

摘　　要：目的:为临床合理使用非甾体抗炎药提供参考。方法:对我院2010年10月-2013年10月非甾体抗炎药的选用情况、各病区使用的构成比及消耗总金额、用药频度(DDDs)、日均费用(DDC)和排序比等相关数据进行统计和分析。结果:临床使用主要以非选择性环氧化酶(COX)抑制剂为主,2011-2013年其使用构成比分别占94.3%、80.5%、82.6%;术后使用主要集中在骨科,占各病区使用构成比的84.9%;消耗总金额居前3位依次为帕瑞昔布、氯诺昔康、氟比洛芬酯,DDC排序分别为1、2、3,排序比分别为0.3、1.5、0.5;3年来口服制剂的DDDs依次占总DDDs的57%、51%、31%。结论:我院非甾体抗炎药在使用种类的选择上与国际趋势相一致,以非选择性COX抑制剂为主,但非甾体抗炎药的DDDs较大,且口服剂型用量的构成比逐年降低,其合理性值得商榷。OBJECTIVE：To provide reference for rational use of non-steroidar anti-inflammatory drugs（NSAIDs）in the clinic. METHODS：The utilization of NSAIDs in our hospital during Oct. 2010-Oct. 2013 was analyzed statistically in terms of drug selection,constituent ratio,total consumption sum,DDDs,DDC and sorting ratio. RESULTS：Nonselective COX inhibitor took up leading place,and constituent ratio were respectively 94.3% and 80.5%,82.6% from 2010 to 2013. NSAIDs were mainly used in orthopedics department after surgery,accounting for 84.92% of its constituent ratios in the ward. Top 3 drugs in the list of consumption sum were parecoxib,lornoxicam and flurbiprofen axetil. DDC sort were 1,2,3 and sorting ratio of 0.3,1.5 and 0.5;in3 years,DDDs of oral formulations accounted for 57%,51% and 31% in total DDDs,respectively. CONCLUSIONS：The type selection of NSAIDs in our hospital is consistent with international trends,and main type is non-selective COX inhibitor;but DDDs of NSAIDs is large and constituent ratio of oral dosage forms decreases year by year;its legitimacy is questionable.

关 键 词：非甾体抗炎药 术后镇痛 应用分析 

分 类 号：R978.1[医药卫生—药品] R969.3[医药卫生—药学]