中药中总黄酮的含量测定方法研究进展  

The Research Progress on Content Determination Methods of Total Flavonoids in TCM

作　　者：任珊珊[1] 包保全[1,2] 毛婷[1] 昌妍希 张屏[1] 斯琴塔娜 

机构地区：[1]内蒙古医科大学药学院,呼和浩特010110 [2]内蒙古民族大学蒙医药学院,通辽028000 [3]内蒙古自治区国际蒙医医院国家制剂中心,呼和浩特010020

出　　处：《北方药学》2015年第3期112-115,共4页Journal of North Pharmacy

基　　金：内蒙古自然科学基金重大项目"基于血清化学和血清药理学的蒙药复方‘查干汤’药效物质基础研究"项目编号:2011ZD13;国家自然科学基金地区项目"基于循证医学理念和血清药物学方法的蒙医瘟疫热病经典方剂‘查干汤’抗流感药效物质基础及其代谢规律研究"项目编号:81460651

摘　　要：黄酮是一类重要的中药有效成分,具有扩冠、护肝、解痉、抗菌、抗炎等多种功效,其含量的测定方法与限度控制是中药及其制剂质量标准的重要内容。随着药物分析研究理论、方法和技术的发展,药品中总黄酮含量测定的研究取得了令人瞩目的成果。本文总结了近十年来相关的研究论文,从样品前处理、测定原理与方法、结果数据处理及对照品的选择4个方面进行综述,为以黄酮为指标性成分的药品质量控制研究提供参考。Flavonoids is a class of important efficacy material base of TCM,with various treatment effect such as expansion of coronary artery,protection of liver,spasmolysis,antibiosis and anti-inflammation,etc. So the content determination methods and limitation of flavonoids in Chinese medical materials and its preparations is an emphasized field in the quality control of TCM. Recently,this field was largely promoted by the growth of new analytic methods and technologies. In this paper we summarized the progress in quantitative analysis of flavonoids in the last 10 years,which would discussed on 4 aspects：the preparation of test sample solution,the measuring principles and methods,the data processing and results and the selection of standard compounds.

关 键 词：总黄酮 含量测定 质量控制 中药 研究进展 

分 类 号：R927.2[医药卫生—药学]