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作 者:崔旭[1]
出 处:《北方药学》2015年第3期130-131,共2页Journal of North Pharmacy
摘 要:目的:观察甲状腺颈丛神经阻滞后,体内甲状腺激素的变化及其对血压、心率影响。方法:选择择期手术无心血管疾患、无情绪紧张、非甲亢患者44例。麻醉采用双侧颈浅、术测颈深的阻滞方法,颈深分别阻滞颈椎3、4、5,每个点采用0.25%布比卡因3~4ml,颈浅8~10ml注射,未加肾上腺素。分别于术前ld、麻醉后5min、15min、30min(切皮前)取血2ml,测定麻醉前、后甲状腺激素(T3,T4、FT3、FT4)值,观察并记录BP及HR的变化。结果:44例患者颈丛神经阻滞5min后,BP、HR开始上升,15min左右达到高峰,30min后开始慢慢下降;与麻醉前比,T4、FT3、FT4均轻度增高,而T3轻度下降(P〉0.05),但均在正常值范围内。结论:颈丛神经阻滞引起部分患者一过性BP升高、HR增快,与甲状腺激素轻微变化无明显关系,原因值得进一步探讨。Objective:To observe the effects of cervical plexus block on blood pressure、heart rate and thyroid hormones.Methods:Forty-four patients without cardiovascular diseases or mental tension or hyperthyroidism were choiced. cervical plexus block was used,each point with 0.25% bupivacaine 3~4ml,injected 8~10ml in superficial cervical plexus no adrenaline blood samples were collected for the measurements of thyroid hormones(T3,T4,F T3,FT4)on one day before anesthesia,at 5,15,and 30 min after completion of cervical plexus block,and BP,HR were recorded at the same time points.Results:BP and HR increased significantly at 5 min after completion of cervical plexus block,reached to peak level at 15 min,and lasted until 30 min,and T3、T4、FT3、FT4 were changed slightly,But were within the normal range Conclusion:The circulatory response to cervical plexus block may not be related to the changes in thyroid hormones. The reason was worthed further discussion
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