芦丁铅的合成及清除自由基活性研究  

Synthesis and Free Radical Scavenging Activity of Pb(Ⅱ)-Rutin Complex

作　　者：郭胜男[1] 翟广玉[1] 渠文涛[2] 张丽雪[1] 王艳[1] 

机构地区：[1]郑州大学护理学院,河南郑州450001 [2]郑州大学药学院,河南郑州450001

出　　处：《化学与粘合》2015年第2期125-128,共4页Chemistry and Adhesion

基　　金：郑州大学国家大学生创新创业训练计划项目(编号:2014xjxm316)

摘　　要：芦丁与铅离子在室温下可以生成性能稳定的配合物。通过紫外光谱、红外光谱分析对其结构进行了表征。通过DPPH法测定了芦丁铅清除自由基的能力,实验结果显示,芦丁铅清除自由基的能力没有芦丁强。在日常生活中经常食用一些含有芦丁的黄酮类食物,如柑橘、草莓、银杏、荞麦等,可清除体内的自由基,使机体免受自由基的损伤,对降低人体内重金属离子的含量起着重要的作用。The complex of Pb （Ⅱ） with rutin was prepared at room temperature. The UV-visible, IR spectrum was used to characterize the struc- ture of the complex. The free radical scavenging activity of the complex was evaluated by using 1,1-diphenyl-2-picrylhydrazyl （DPPH） radical scav- enging method. The experiment showed that the free radical scavenging activity of Pb（II）-rutin complex was less effective than that of the rutin. Sup- plementing diet which is rich in rutin and other flavonoids in daily life, such as citrus, strawberry, ginkgo, buckwheat, etc., could be contribut to re- moving free radicals and heavy metal ions in our body and made the body be safe from the damage of free radical.

关 键 词：芦丁 芦丁铅配合物 合成 表征 清除 自由基 

分 类 号：R979.3[医药卫生—药品]