钙离子拮抗剂类降压药的临床应用及不良反应  

Calcium Channel Blockers of Clinical Application and Adverse Reactions

作　　者：王宇[1] 徐颖颖[1] 张相彩[1] 郑韧[1] 朱圣婷 王怀冲[1] 

机构地区：[1]杭州市红十字会医院药剂科,杭州310006

出　　处：《中国现代应用药学》2015年第3期385-390,共6页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的对钙离子拮抗剂在临床中的临床应用及不良反应做系统的分析,总结钙离子拮抗剂在临床中的应用及注意事项,为药师在临床用药监测中提供了理论支持。方法通过查阅文献的方式,系统学习钙离子拮抗剂的临床应用及不良反应。结果钙离子拮抗剂广泛应用于心血管等多种疾病,其不良反应有心律失常、低血压、房室传导阻滞、心力衰竭、牙龈增生、外周水肿、便秘等。药物使用应关注其常见和罕见的不良反应,促进合理用药。结论药物在使用过程中,不仅要注重药物的药理作用及临床疗效,最好在使用之前就预见药物的不良反应,才能做到及时防治,最大地发挥药物疗效。OBJECTIVE To understand the calcium channel blockers in clinical application and precautions for pharmacists to provide a theoretical support for clinical drug monitoring by reviewing calcium channel blockers in clinical application and adverse reactions of the system.METHODS The literature of the way,the systematic study of clinical applications and adverse reactions calcium channel blockers were reviewed.RESULTS Calcium channel blockers were widely used in cardiovascular and other diseases,adverse reactions included arrhythmia,hypotension,atrioventricular block,heart failure,gingivalhyperplasia,peripheral edema,constipation.Its common and rare adverse reactions should be focused to promote rational drug use.CONCLUSION The use of a class of drugs in the process,not only to focus on the pharmacological effects of drugs and clinical efficacy,better before using foresaw adverse drug reactions,in order to achieve prevention and treatment,the efficacy of the biggest play of the drug.

关 键 词：钙离子拮抗剂 降压 临床应用 不良反应 心血管系统 

分 类 号：R969.3[医药卫生—药理学]