多指标正交优选大腹皮饮片切制工艺  

Optimization of Preparation of Cutting-processed Arecae Pericarpium with Multi-index Orthogonal Method

作　　者：郁红礼[1,2] 汤丽娟[1] 吴皓[1,2] 毛春芹[1] 陆兔林[1] 毛善虎 

机构地区：[1]南京中医药大学药学院,江苏南京210023 [2]江苏省中药炮制重点实验室/国家教育部中药炮制规范化及标准化工程研究中心,江苏南京210023

出　　处：《中药材》2014年第12期2178-2181,共4页Journal of Chinese Medicinal Materials

基　　金：国家药典委标准提高课题(2011-779;780);江苏省优势学科建设工程资助项目

摘　　要：目的:优选大腹皮饮片切制工艺。方法:采用正交试验法,以4种生物碱(槟榔碱、槟榔次碱、去甲槟榔碱、去甲槟榔次碱)含量及水溶性煎出物得率为指标,采用相关系数综合评分法,选择切制宽度、烘干温度和烘干时间为考察因素,优化大腹皮饮片的炮制工艺。结果:优选出的炮制工艺为:大腹皮药材抢水洗后,润透,纵切1 cm段,50℃烘2.5 h。结论:优选出的大腹皮炮制工艺稳定可行,重现性好。Objective： To optimize the preparation of cutting-processed Arecae Pericarpium by the orthogonal method. Methods：With four alkaloids such as arecoline,arecaidine,guvacoline,guvacine and yield of water-soluble decoction as indexes,a L9（34） orthogonal test was adopted to compare the effect of different factors on cutting-processed Arecae Pericarpium. Results： According to the finalized optimal process,Arecae Pericarpium was washed quickly,moisturized,chopped lengthwise in 1 cm segment and then dried for 2. 5h at 50 ℃. Conclusion： The optimal process method is reasonable and reliable,it can provide basis for the preparation of cutting-processed Arecae Pericarpium.

关 键 词：大腹皮 炮制工艺 正交设计 生物碱 水溶性煎出物得率 

分 类 号：R282.4[医药卫生—中药学]