草莓番石榴叶化学成分研究  

Study on Megastigmane Glycosides and Lignan Constituents from Leaves of Psidium littorale

作　　者：彭财英[1] 刘建群[1] 舒积成[1] 张锐[1] 

机构地区：[1]江西中医药大学,江西南昌330004

出　　处：《中药材》2014年第12期2201-2203,共3页Journal of Chinese Medicinal Materials

基　　金：国家自然科学基金(81360630;81102788);江西省教育厅课题(GJJ13585);江西省卫生厅课题(2012A025);江西省自然科学基金(20114BAB215041)

摘　　要：目的：研究草莓番石榴叶的化学成分。方法：采用正反相硅胶、凝胶柱色谱、薄层色谱等手段分离,波谱法进行结构鉴定。结果：从草莓番石榴叶中分离得到4个四甲基环己烯型单萜苷类化合物：Bridelionoside B（1）、Euodinoside E（2）、（3S,5R,6R,7E,9S）-Megastignan-7-ene-3,5,6,9-tetrol-9-O-β-D-glucopyranoside（3）、Bridelionoside C（4）,3个木脂素类化合物：（-）-异落叶松树脂醇3-α-O-β-D-葡萄糖苷（5）、（-）-5＇-甲氧基-异落叶松树脂醇3-α-O-β-D-葡萄糖苷（6）、Dihydrodehydrodiconiferyl alcohol 4-O-β-D-glucopyranoside（7）。结论：化合物1~7均为首次从草莓番石榴叶中分离得到。Objective： To study the chemical constituents of the leaves of Psidium littorale. Methods： The constituents were isolated with silica gel column chromatography and the structures of these compounds were elucidated on the basis of spectral analysis. Results：Four megastigmane glycosides and three lignans were isolated and their structures were identified as Bridelionoside B（1）,Euodinoside E（2） 、（3S,5R,6R,7E,9S）-Megastignan-7-ene-3,5,6,9-tetrol 9-O-β-D-glucopyranoside（3）,Bridelionoside C（4）,（-）-Isolariciresinol 3-α-O-β-D-glucopyranoside（5）,（-）-5＇-methoxy-Isolariciresinol 3-α-O-β-D-glucopyranoside（6） and dihydrodehydrodiconiferyl alcohol 4-O-β-D-glucopyranoside（7）. Conclusion： Compounds 1 ~ 7 are isolated from this plant for the first time. The results have provided the scientific basis for further exploitation of Psidium littoratle.

关 键 词：草莓番石榴 化学成分 四甲基环己烯型单萜苷 木脂素 

分 类 号：R259.125[医药卫生—中西医结合]