尿路结石和尿路感染的关系分析  

The relationship analysis of urinary calculus and urinary tract infection

作　　者：郑晓秋[1] 王万东[1] 张继承[1] 熊雨 

机构地区：[1]四川省宜宾市第二人民医院,四川宜宾644000

出　　处：《中国现代医学杂志》2015年第7期92-95,共4页China Journal of Modern Medicine

摘　　要：目的探讨尿路结石和尿路感染的关系。方法 100例实施腹腔镜或开腹手术取石的尿路结石患者根据是否发生尿路感染分为感染性结石组和对照组。对比两组患者的异常尿常规患者例数、阳性中段尿患者例数、阳性消毒棉拭子患者例数和尿路感染患者例数,并对两组患者的结石成分进行分析。结果 100例尿路结石患者中发现感染性结石36例(36.0%),感染细菌的分布主要是:大肠埃希菌39例(39.0%),表皮葡萄球菌27例(27.0%),奇异变形杆菌12例(12.0%)。感染性结石组患者的异常尿常规患者例数、阳性中段尿患者例数、阳性消毒棉拭子患者例数和尿路感染患者例数均明显高于对照组,差异具有统计学意义(P<0.05)。感染性结石组的结石成分主要为六水磷酸镁铵,占61.1%;对照组的结石主要成分为草酸钙结石(48.4%)和尿酸结石(35.9%)。经比较两组患者间的结石成分均差异存在,感染性结石组的六水磷酸镁铵、羟基磷灰石与碳酸磷灰石的发生率明显高于对照组,而草酸钙结石和尿酸结石的出现率感染性结石组明显低于对照组,差异具有统计学意义(P<0.05)。结论尿路感染能够导致尿路结石;而尿路结石又可以促进尿路感染,六水磷酸镁铵是最容易发生感染的结石。【Objective】To explore the relationship between urinary stones and urinary tract infection.【Methods】100 cases of urinary calculi patients with the implementation of laparoscopic or open operation stone based on the occurrence of urinary tract infection were divided into infection group and control group. The number of patients with abnormal urine routine, the number of patients with positive urine, the number of patients with positive sterilized cotton swab, the number of patients with urinary tract infection, and stone composition analysis were compared between the two groups.【Results】100 cases of urinary calculi were found in 36 patients（36.0%）, the distribution of calculi infection bacterial infection is mainly： 39 cases were Escherichia coli（39.0%）, staphylococcus epidermidis in27 cases（27.0%）, proteus mirabilis in 12 cases（12.0%）. Infected patients were abnormal urine routine, the number of patients with positive urine, the number of patients with positive sterilized cotton swab, the number of patients with urinary tract infection were significantly higher than those in control group, with statistically significant difference（P〈0.05）. Stone composition of infection group was mainly six water ammonium magnesium phosphate, accounted for 61.1%; the main component of control group of stones was calcium oxalate stones（48.4%） and uric acid stones（35.9%）. The stone composition was significantly differences between the two groups, the incidence of infection group six water magnesium ammonium phosphate, hydroxyapatite and carbonated apatite was higher than that of control group, and the emergence of calcium oxalate and uric acid calculi rate of infection group was significantly lower than the control group（P〈0.05）. 【Conclusion】Urinary tract infection can lead to urinary tract stones and urinary calculi can promote urinary tract infection, six water magnesium ammonium phosphate is the most prone to infection stones.

关 键 词：尿路结石 尿路感染 感染性结石 

分 类 号：R691.4[医药卫生—泌尿科学]