某地区医院133例药品不良反应报告分析  

133 Cases of Adverse Drug Reactions Reports in One Hospital in A City

作　　者：赵明琴[1] 何文富[1] 李雯[1] 曾永保[1] 孙浩岩[1] 

机构地区：[1]四川省宜宾市第一人民医院药剂科,四川宜宾644000

出　　处：《中国药业》2015年第6期48-49,共2页China Pharmaceuticals

摘　　要：目的分析医院药品不良反应(ADR)的特点和规律,促进临床合理用药。方法依据《药品不良反应报告和监测管理办法》,对医院133例ADR报表进行分析。结果涉及ADR药物82种,抗感染药物居首位(30.08%),其次为中成药(16.54%);静脉给药是引发ADR的主要途径,占比66.17%;ADR的临床表现以皮肤及其附件损害(36.84%)为主,其次是消化系统损害(22.50%)。结论临床应注意合理用药,以避免或减少ADR发生。Objective To analyze the characteristics and rule of adverse drug reactions（ ADR） in a hospital in order to promote the rational drug use. Methods 133 cases of ADR reports in our hospital were analyzed according to the Reporting and Monitoring Administration Measure on ADR. Results The drugs involving ADR were 82 varieties,the anti- infection drugs stood the first on the list（ 30. 08%）,followed by the traditional Chinese patent medicines（ 16. 54%）; the intravenous administration was the main pathway causing ADR（ 66. 17%）; the clinical manifestations of ADRs were dominated by the lesion of skin and the appendants（ 36. 84%）,followed by the lesion of digestive system（ 22. 50%）. Conclusion The rational drug use should be paid more attention to avoid and reduce the ADR occurrence.

关 键 词：药品不良反应 药物监测 合理用药 

分 类 号：R954[医药卫生—药学] R952