3种无创模式机械通气治疗新生儿呼吸窘迫综合征的疗效  

Curative effect on three non-invasive modes of mechanical ventilation in treatment of neonatal respiratory distress syndrome

作　　者：刘郴州[1] 关浩锋[1] 

机构地区：[1]广东省江门市中心医院儿科重症监护病区,529030

出　　处：《实用医学杂志》2015年第5期734-736,共3页The Journal of Practical Medicine

基　　金：广东省医学科研基金资助课题(编号:A2012727);江门市科技计划项目[编号:江科(2012)107号-97]

摘　　要：目的:比较无创CPAP、无创SIMV、无创Bi PAP通气治疗新生儿呼吸窘迫综合征(RDS)的疗效。方法:采用回顾性研究,对2010年3月至2014年3月在我科住院使用过上述3种机械通气模式之一治疗的且符合病例纳入标准的162例新生儿的临床资料进行分析,比较它们的疗效。结果:无创CPAP组53例,无创SIMV组60例,无创Bi PAP组49例,3组之间性别比、出生胎龄、出生体重比较均无统计学差异(均P>0.05);其中无创CPAP组、无创SIMV组、无创Bi PAP组治疗成功病例数分别为38、53、44例,无效病例数分别15、7、5例,3组疗效比较不全相同(P<0.05),其中无创SIMV组与无创Bi PAP组比较无统计学差异(P>0.05),无创SIMV组与无创Bi PAP组明显优于无创CPAP组(均P<0.05)。结论:无创SIMV、无创Bi PAP通气治疗新生儿RDS的疗效无统计学差异,但较无创CPAP疗效较好,可作为优先选择。Objective To investigate the curative effect on non-invasive CPAP and SIMV and BiPAP mechanical ventilation in treatment of NRDS. Methods A retrospective study was initiated on clinical data of 162 neonates, who were hospitalized from March 2010 to March 2014 in Jiangmen Central Hospital and underwent the above three modes of non-invasive mechanical ventilation treatment. All cases met the setting standard, and their curative effects were contrasted. Results 53 cases were treated by non-invasive CPAP, 60 cases were operated by non-invasive SIMV, 49 cases were done by non-invasive BiPAP. Among the three groups, the comparison on sex ratio,gestational age of birth and birth weight showed no difference （P 〉 0.05）. The number of effective cases in three groups was 38, 53 and 44 respectively, and the number of invalid cases was 15, 7 and 5 respectively. Among three groups, the curative effect was significant （P 〉 0.05）, curative effect of non-invasive SIMV group showed no difference （P 〉 0.05） compared with that of non-invasive BiPAP group, curative effect of non-invasive SIMV group and non-invasive BiPAP group was better than that of non-invasive CPAP group （P 〉 0.05）. Conclusion Curative effects of non-invasive SIMV and non-invasive BiPAP for NRDS showed no difference. However, their curative effect is better than that of non-invasive CPAP, which indicates that they can be better choices.

关 键 词：机械通气 呼吸窘迫综合征 治疗 新生儿 

分 类 号：R722.1[医药卫生—儿科]