大型血小板比率与房颤患者脑卒中的相关性  

Correlation analysis of large-platelet ratio(P-LCR) and stroke in patients with atrial fibrillation

作　　者：王占胜[1] 付强[1] 李铎[1] 李根[1] 蔡金龙[1] 徐立庆[1] 张木[1] 齐霁[1] 

机构地区：[1]沈阳市第四人民医院心内二科,110031

出　　处：《实用医学杂志》2015年第5期760-761,共2页The Journal of Practical Medicine

摘　　要：目的:探讨大型血小板比率(P-LCR)与房颤患者脑卒中的相关性。方法:连续入选152例房颤患者,依据是否伴发脑卒中并发症分为脑卒中组和非脑卒中组,并对患者临床特征及相关血液检查指标P-LCR进行Logistic回归分析。结果:入选的患者中,有脑卒中并发症者47例,无脑卒中并发症者105例。单因素分析显示,两组间年龄、糖尿病史、高血压病史、降脂治疗及P-LCR差异具有统计学意义(P<0.05);Logistic回归分析显示,年龄、糖尿病史及P-LCR为房颤患者脑卒中的独立危险因素。结论:年龄、糖尿病史及P-LCR为房颤患者脑卒中发生的独立危险因素。Objective To investigate the correlation between large platelet ratio （P-LCR） and stroke in patients with atrial fibrillation. Methods 152 consecutive patients with atrial fibrillation were selected and divided into two groups according to whether accompanying stoke or not. Clinical features of patients and blood test indicator P-LCR were analyzed by Logistic regression analysis. Results In total, 152 subjects, including 47 patients with stoke and 105 patients without stoke,were included in the study. Univariate analysis showed that the difference in age, diabetes, hypertension, lipid-lowering therapy and P-LCR between two groups was statistically significant （P 〈 0.05）. Logistic regression analysis showed that age, diabetes and P-LCR were independent risk factors of stroke in patients with atrial fibrillation. Conclusions Age, diabetes and P-LCR are independent risk factors of stroke in patients with atrial fibrillation.

关 键 词：心房颤动 卒中 大型血小板比率 

分 类 号：R541.75[医药卫生—心血管疾病] R743.3[医药卫生—内科学]