坦索罗辛联合热淋清在输尿管下段结石排石治疗中的作用研究  

The research on the role of tamsulosin combined with relinqing in treating lower ureteral stones

作　　者：李琛[1] 吴岩[1] 于得水[1] 董坚[1] 冯宁翰[1] 

机构地区：[1]无锡市第二人民医院,江苏无锡214002

出　　处：《国际泌尿系统杂志》2015年第2期209-211,共3页International Journal of Urology and Nephrology

摘　　要：目的 探讨坦索罗辛联合热淋清对输尿管下段结石排石治疗和疼痛缓解的疗效.方法 将161例输尿管下段结石患者随机分为三组：对照组56例,给予一般治疗;A组48例,给予坦索罗辛0.4mg,每日一次;B组57例,给予坦索罗辛0.4mg,每日一次和热淋清8g,每日三次.所有患者观察至结石排出或治疗后两周.结果 对照组、A组和B组的排石率分别为12.50％、41.67％和61.40％;排石时间分别为10.51±1.98d、7.48±2.16d和5.76±2.23d;肾绞痛发生率分别为83.93％、43.75％和24.56％.在排石率、排石时间及肾绞痛发生率上,A、B组同对照组比较差异有统计学意义（P＜0.05）,且B组与A组比较差异亦有统计学意义（P＜0.05）.结论 坦索罗辛联合热淋清能提高下段输尿管结石的排出率,缩短排石时间,减轻患者痛苦,是一种理想的中西结合排石治疗方法,值得临床应用.Objectives To investigate the efficacy of tamsulosin combined with Relinqing in treating lower ureteral stones.Methods 161 patients with lower ureteral stones were randomly divided into three groups.The control group（n =56） was given general treatment only,A group（n =48） was given tamsulosin,and B group（n =57） was given tamsulosin combined with Relinqing.The course of treatment was until stone clearance or for a maximum of 2 weeks.The lithagogue rate,lithagogue time and nephrocolic rate were recorded.Results The lithagogue rate,lithagogue time and nephrocolic rate of B group was 61.40%,5.76 ± 2.23d and 24.56%,which had statistical significant difference when compared to A group（41.67%,7.48 ± 2.16d and 43.75%,P 〈 0.05） or control group（12.50%,10.51 ± 1.98d and 83.93%,P 〈 0.05）.Conclusions Tamsulosin combined with Relinqing can increase the lithagogue rate,shorten the lithagogue time,and decrease the nephrocolic rate in lithagogue treatment of lower urinary stones.

关 键 词：输尿管结石 肾上腺素能Α拮抗剂 

分 类 号：R693.4[医药卫生—泌尿科学]