血清胆固醇脂蛋白水平对胆囊胆结石中胆固醇浓度的影响  

作　　者：任清河 崔宏伟[2] 

机构地区：[1]武警内蒙古边防总队医院普通外科,010051 [2]内蒙古医科大学附属医院临床医学研究中心,010050

出　　处：《浙江临床医学》2015年第3期351-353,共3页Zhejiang Clinical Medical Journal

摘　　要：目的探讨血清总胆固醇（TC）、脂蛋白水平对胆囊胆结石中胆固醇浓度的影响。方法检测150例胆石症患者以及50例健康对照组人群的血清TC、低密度脂蛋白水平（LDL）、高密度脂蛋白水平（HDL）。采用傅立叶红外光谱法测定结石中胆固醇含量。结果胆囊结石患者较正常组患者的血清TC、LDL水平升高，HDL水平降低，差异有统计学意义（P〈0．05）。伴有较高水平的血清TC、LDL与高胆固醇结石形成率相关（P〈0．05），与胆结石中胆固醇浓度相关（P〈0．05）。而伴有较低水平的血清HDL与胆囊胆固醇结石形成及胆囊结石胆固醇浓度无关（P〉0．05）。结论血清TC、LDL水平的异常与胆囊胆固醇结石的形成有一定关系。Objective To discuss the effects of the serum total cholesterol, Low-density lipoproteins and high-density lipoproteins serum cholesterol, LDL, and HDL levels on gallstone cholesterol concentration. Methods The levels of serum total cholesterol, LDL, and HDL of 150 patients with cholelithiasis and 50 cases of healthy Volunteers were examined using automatic biochemical analyzer. And the gallstones were examined thro μ gh Fourier transform infrared spectrometry. Results High serum cholesterol and LDL levels were associated with high cholesterol stone rates （ P〈0.05 ） . Similarly, high serum cholesterol and LDL levels were correlated with high gallbladder stone cholesterol concentrations （ P〈0.05 ） . In contrast, low serum HDL levels do not seem to affect the occurrence of gallbladder cholesterol stones （P〉0.05） or gallbladder stone cholesterol concentrations （ P〉0.05 ） . Conclusions There was a certain relationship between the abnormal in serum total cholesterol, Low-density lipoproteins, high-density lipoproteins and the formulation of gallbladder cholestrol stone.

关 键 词：血清胆固醇 低密度脂蛋白水平 高密度脂蛋白水平 胆固醇胆结石 

分 类 号：R446.112[医药卫生—诊断学]