HMQC和HMBC在苯乙醇酯裂环环烯醚萜苷结构测定中的应用  

HMQC and HMBC in the Structure Determination of Benzene Ethyl Ester Iridoid Glycosides

作　　者：李坤威[1] 张剑[1] 张海艳[2] 赵天增[2] 

机构地区：[1]中国标准化研究院,北京100010 [2]河南省生物技术开发中心,郑州450002

出　　处：《河南科学》2015年第3期336-337,共2页Henan Science

基　　金：质检公益性行业科研专项经费资助项目(2012104019-1)

摘　　要：在苯乙醇酯裂环环烯醚萜苷中,其苯环上6个碳的归属文献中常出现错误,从而导致化合物结构测定的错误.本文先根据偶合常数大小和峰分裂数目将H-4″、H-7″、H-8″明确归属,再利用HMQC和HMBC技术确定苯环6个碳的归属,然后再利用糖苷中碳化学位移配糖效应确定葡萄糖在苯环上的取代位置.In the hteratures about benzene ethyl ester secoiridoid glycosides, the assignments of the six carbons belonging to the benzene ring were usually in errors, resulting in the wrong structure. In this paper, according to the coupling constant size and peak splitting number, H-4″, H-7″, H-8″ could be clearly attributed. Then, by using HMQC and HMBC technique, the chemical shifts of the six benzene carbons were determined. Finally, the carbon chemical shift effect of the glycoside was used to ascertain the substituent positions on the benzene ring.

关 键 词：NMR 归属 HMQC HMBC 苯乙醇酯裂环环烯醚萜苷 

分 类 号：O629[理学—有机化学]