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机构地区:[1]内江市第一人民医院儿科,四川内江641000
出 处:《临床和实验医学杂志》2015年第6期504-507,共4页Journal of Clinical and Experimental Medicine
摘 要:目的对儿童支气管哮喘与母孕期及新生儿期相关危险因素进行分析。方法以2012年3月至2014年1月确诊并治疗的127例儿童支气管哮喘患儿为观察组;随机选择同期的152例正常儿童作为对照组。对所有入选对象母孕期及新生儿期的相关资料进行调查。结果单因素分析结果提示观察组和对照组早孕期发热、孕早期服药史、妊娠高血压综合征、1分钟Apgar评分<7分、出生体重<2 500 g、孕龄<37周、剖宫产率相比差异有统计学意义(P<0.05);对单因素分析有意义的因素进行多因素分析,结果提示早孕期发热、胎龄<37周及剖宫产结束分娩是儿童支气管哮喘发生的独立危险因素。结论早孕期发热、胎龄<37周及剖宫产结束分娩是儿童支气管哮喘发生的独立危险因素。了解这些因素,早期进行干预对降低儿童支气管哮喘的发生率有重要的意义。Objective To analyze related risk factors of bronchial asthma in children and maternal and neonatal periods. Methods A total of 127 pediatric patients with bronchial asthma during March 2012 to January 2014 were diagnosed and listed in observation group,and 152 normal children in the same period were randomly selected as control group. All relevant information on selected objects during pregnancy and neonatal period had been studied. Results Single factor analysis indicated that the difference in early pregnancy period,fever,history of medication,pregnancy induced hypertension syndrome,1 minute Apgar scores 7,birth weight 2 500 g,gestational age 37 weeks and the rate of cesarean section compared between these 2 groups was statistically significant( P 0. 05); the result of multi-factors analysis suggested that fever in early pregnancy period,gestational age 37 weeks and caesarean birth were independent risk factors for bronchial asthma in children. Conclusion Fever in early pregnancy period,gestational age 37 weeks and caesarean birth were independent risk factors for occurrence of bronchial asthma in children. It is important to understand these factors that early intervention to reduce the incidence of bronchial asthma in children is important.
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