颈动脉粥样硬化与同型半胱氨酸、血脂、血糖、尿酸相关性研究  

The correlation research of relationship between carotid atherosclerosis occurrence and homocysteine,blood lipids,blood glucose and uric acid in physical examination

作　　者：施洪[1] 郭润达[1] 刘辉强[1] 陈忠锃 黄燕燕[1] 

机构地区：[1]南京军区福州总医院健康体检管理中心

出　　处：《中国实用神经疾病杂志》2015年第1期38-40,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探索颈动脉粥样硬化形成与同型半胱氨酸、血脂、血糖、尿酸的相关性,为早期干预提供依据。方法选择我院健康体检管理中心(体检中心)2011-04—2012-07健康体检颈动脉彩色多普勒超声检查的体检者175例,根据检查结果将体检者分为动脉粥样硬化(AS)组114例与无颈动脉硬化组61例,同时记录检测的同型半胱氨酸(Hcy)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、空腹血糖(FPG)、尿酸(UA)值,应用SPSS17.0软件进行统计学处理。结果 AS发生于双侧颈动脉分叉处57例(50%),右侧颈动脉分叉处8例(7.0%),双侧颈内动脉32例(28.07%)。体检者的AS以早期硬化(内膜增厚)68例(59.64%),其次是硬斑27例(23.68%),混合斑19例(16.67%)。AS组的Hcy、LDL-C、FPG、UA显著高于无硬化组(P<0.05),经Logistic多因素回归分析筛选与AS的相关因素是Hcy、TG、LDL-C、FPG(P<0.05)。结论 AS形成是多种危险因素共同作用的结果,其中Hcy、TG、LDL-C、FPG是AS的独立危险因素,应予早期干预。Objective To investigate the correlation between carotid atherosclerosis occurrence and homocysteine, blood lipids, blood glucose and uric acid in physical examination. Methods 175 cases of physical examination with carotid color Doppler ultrasound from April 2011 to July 2012 were divided into carotid atherosclerosis （AS） group （n = 114） and non-carotid atherosclerosis group （n=61）. The homocysteine （Hcy）, total cholesterol （TC）, triglyceride （TG）, high density lipoprotein （HDL-C） low-density lipoprotein （LDL-C）, fasting plasma glucose （FPG） and uric acid （UA） values in two groups were detected. Results The Hcy, LDI=C, FPG and UA values in AS group were significantly higher than these in non-AS group （P〈 0.05）. Conclusion Hey, TG, LDL-C and FPG are the independent risk factors for AS, which should be early intervened.

关 键 词：颈动脉粥样硬化 彩色超声 同型半胱氨酸 血脂 血糖 尿酸 

分 类 号：R541.4[医药卫生—心血管疾病]