NFκB1-94insdelATTG位点基因多态性、血浆NF-κB水平与急性冠脉综合征的相关性  

Correlation between NFκB1-94insdel ATTG gene polymorphism,serum NF-κB level and acute coronary syndrome

作　　者：王丽[1] 叶强[1] 范忠才[1] 

机构地区：[1]泸州医学院附属医院心内科,四川省泸州市643000

出　　处：《临床合理用药杂志》2015年第9期178-180,共3页Chinese Journal of Clinical Rational Drug Use

摘　　要：随着人们生活水平的提高,人们对医疗技术有了更高的要求。同时人们饮食习惯的改变导致心血管疾病发病率呈逐年增高趋势。研究表明,NFκB1-94insdel ATTG位点基因多态性、血浆NF-κB水平可能与急性冠脉综合征的发生、发展具有一定的相关性,影响着疾病进展及斑块稳定性。本文对NFκB1-94insdel ATTG位点基因多态性、血浆NF-κB水平与急性冠脉综合征的相关性进行综述,为治疗急性冠脉综合征提供参考。With the improvements of living standard,the requirements for the hospital medical technology is higher and higher. And with the changes of diet,the morbidity of cardiovascular diseases is increasing. NFκB1-94insdelATTG gene polymorphism and serum NF-κB level are might be correlated with the occurrence and development of acute coronary syndrome, can affect the stability of plaque and progression of disease. This paper reviewed the correlation between NFκB1-94insdelATTG gene polymorphism,serum nf—Κb level and acute coronary syndrome,to provide references for treating acute coronary syn-drome.

关 键 词：急性冠脉综合征 多态性 单核苷酸 综述 

分 类 号：R541.4[医药卫生—心血管疾病]