不同热处理温度下纳米羟基磷灰石/聚酰胺66多孔支架制备及力学性能研究  

Fabrication and mechanical property of nano-hydroxyapatite/polyamide66 porous scaffolds under different temperature

作　　者：黄棣[1] 袁文凤[2] 杜晶晶[1] 易生泰 郭美卿[1] 魏延[1] 

机构地区：[1]太原理工大学力学学院,太原030024 [2]周口职业技术学院机电工程系,周口466000

出　　处：《化工新型材料》2015年第3期77-79,共3页New Chemical Materials

基　　金：国家自然科学基金(51301117);山西省高等学校科技创新基金(2013111);山西省青年科技基金(2013021014-2)

摘　　要：热处理温度是热致相分离法制备多孔支架材料的关键因素。在不同热处理温度下(60℃、75℃和90℃)制备了纳米羟基磷灰石/聚酰胺66(n-HA/PA66)复合多孔支架材料。对比研究了不同热处理温度下制备的多孔支架孔隙结构、孔隙率及力学性能。结果表明:处理温度对多孔支架的孔隙结构,孔隙率,力学性能有显著的影响,随着温度的升高,多孔支架的孔隙率、平均孔径升高,贯通性改善,但弹性模量和屈服极限降低。多孔支架的热处理温度为75℃时,其孔径、孔隙率和力学性能与天然松质骨相当,是较为理想的骨组织工程支架材料。The heat treatment temperature is the key factor to prepare scaffold by thermally induced phase separation method. n-HA/PA66 composite porous scaffolds were prepared at different temperatures（60℃, 75℃ and 90℃）. The scaffolds prepared under different processing temperatures with different pore structure, porosity and mechanical property were compared. The results showed that different treatment temperature had significant influence on the pore structure, porosity and mechanical property. The porosity and the average pore size of the scaffold increased with increasing temperature. However, the elastic modulus and field limit showed the opposite effect. By comparison,the optimal heat treatment temperature was 75℃. The pore size, porosity and mechanical properties were similar to natural cancellous bone, and the scaffolds showed the potential application in hone tissue engineering.

关 键 词：多孔支架材料 纳米羟基磷灰石 聚酰胺 复合材料 力学性能 

分 类 号：R318.08[医药卫生—生物医学工程]