全身静脉和腹腔热灌注双途径化疗联合体外热疗治疗晚期卵巢癌的疗效观察  被引量:3

Observation on the therapeutic effect of intravenous and intraperitaneal hyperthermic perfusion chemotherapy combined with hyperthermia in vitro dual approach in the treatment of advanced ovarian cancer

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作  者:张群[1] 杨麒麟[1] 

机构地区:[1]资阳市人民医院肿瘤科,四川资阳641300

出  处:《医学美学美容(中旬刊)》2015年第2期28-29,共2页

摘  要:目的:探讨全身静脉和腹腔热灌注双途径化疗联合体外高频热疗对晚期卵巢癌的疗效及毒副反应。方法:56例晚期卵巢癌患者,全部病例均伴有腹水,合并有局部疼痛50例,合并有腹腔种植转移癌结节36例。予以金身静脉和腹腔置管灌注双途径化疗联合体外高频热疗,观察评价其疗效及毒副反应。结果:56例患者近期疗效较为显著,腹水控制:显效(9/56)16.7%,有效(28/56)50.0%,总有效率(37/56)66.7%;疼痛控制:显效(15/50)30.0%,有效(27/50)54.0%,总有效率(42/50)84.0%;腹腔种植癌结节控制:显效(10/36)27.8%,有效(15/36)41.7%,总有效率(25/36)69.5%。结论:全身静脉和腹腔热灌注双途径化疗联合体外热疗治疗晚期卵巢癌是一种行之有效的,安全的姑息治疗手段。Objective: To investigate the effect and adverse reaction of intravenous and intraperitoneal hyperthennic double way chemotherapy combined with extracorporeal high - frequency hyperthermia for advanced ovarian cancer. Methods: 56 cases of patients with advanced ovarian cancer, all eases were accompanied by ascites, accompanied with local pain in 50 cases, combined with peritoneal metastasis cancer nodules in 36 cases. Be intravenous and intraperitoneal perfusion chemotherapy combined with external high frequency thermotherapy in double catheter, evaluate the efficacy and toxicity of observation. Results: 56 patients of recent curative effect is more significant, ascites control: (9/56) 16.7%, markedly effective (28/56) of 50%, the total efficiency of 66.7% (37/56) ; pain control effect : (15/50) 30% (27/50), effective 54%, the total efficiency of 84% (42/50) ; peritoneal cancer nodules ( control : effective 10/36) 27.8% ( 15/36), effective 41.7%, the total efficiency of 69.5% (25/36). Conclusion: intravenous and intraperitaneal hyperthermic perfusion chemotherapy combined with hyperthermia in vitro dual approach in the treatment of advanced ovarian cancer is a kind of effective, safe palliative treatment.

关 键 词:腹腔热灌注化疗 热疗 卵巢癌 

分 类 号:R969.4[医药卫生—药理学]

 

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