针灸治疗实证眩晕的Meta分析  

Meta Analysis of Acupuncture Treatment for Vertigo with Excess Syndrome

作　　者：王凤蕊[1] 汤国娟[1] 叶玲[1] 李国灿[1] 俞国尧[1] 

机构地区：[1]杭州市萧山区第一人民医院,杭州311200

出　　处：《上海针灸杂志》2015年第3期265-268,共4页Shanghai Journal of Acupuncture and Moxibustion

摘　　要：目的系统评价针灸治疗实证眩晕的临床疗效及其安全性。方法全面检索近年来已发表的针灸治疗实证眩晕的中英文文献,然后将检索到的文献对符合纳入标准的随机对照试验进行质量评价和资料提取,最后对纳入的研究进行Meta分析。结果最终10篇随机对照试验共688例患者纳入本试验,Cochrane系统评价员手册5.1评价文献质量偏低,Meta分析显示针灸治疗实证眩晕的有效率优于单纯西药[M-H OR 4.84,95%CI(2.39,9.81),P<0.0001];针刺配合中药优于单纯中药[M-H OR 3.82,95%CI(2.06,7.10),P<0.0001];眩晕症状及功能评分显示,治疗第3天[MD 4.66,95%CI(2.97-6.35)],治疗第7天[MD0.95,95%CI(0.03-1.86)],治疗第14天[MD 0.89,95%CI(0.71-2.49)]。治疗第3天和第7天两组患者的眩晕症状与功能评估积分对比有显著性差异,第14天两组的积分无显著性差异。结论针灸或针灸结合中药治疗实证眩晕有效,安全性高,但尚需开展高质量、多中心、大样本的RCT研究进行验证和支持。Objective To systematically assess the clinical efficacy and safety of acupuncture treatment for vertigo with excess syndrome. Methods Chinese and English literature about acupuncture treatment of vertigo with excess syndrome published in recent years was comprehensively searched. The quality of the retrieved literature meeting the inclusion criteria of randomized controlled trial was assessed and its data was collected. A Meta analysis of the included studies was carried out. Results Finally, 10 articles with randomized controlled trials containing a total of 688 patients were included in the analysis. The included literature was assessed at lower quality using Cochrane evaluation member manual 5.1. A Meta analysis showed that the efficacy rate of acupuncture treatment for vertigo with excess syndrome was higher than that of Western drugs alone [M-H OR 4.84, 95%CI （2.39, 9.81）, P（0.0001]. Combined acupuncture and Chinese herbal medicine was superior to Chinese herbal medicine alone [M-H OR 3.82, 95%CI （2.06, 7.10）, P（0.0001]. Vertigo symptom and function scoring showed day 3 of treatment [MD 4.66, 95%CI （2.97, 6.35）], day 7 of treatment [MD 0.95, 95%CI （0.03, 1.86）] and day 14 of treatment [MD 0.89, 95%CI （0.71, 2.49）]. There were statistically significant differences in the vertigo symptom and function scores between the two groups of patients at day 3 and 7 of treatment. There were no statistically significant differences in the scores between the two groups of patients at day 14 of treatment. Conclusions Acupuncture or combined acupuncture and Chinese herbal medicine are effective and highly safe in treating vertigo with excess syndrome, but high-quality, multi-center and large-sample RCT studies still need to be conducted for validation and support.

关 键 词：针灸疗法 眩晕 实证 META分析 文献研究 

分 类 号：R246.1[医药卫生—针灸推拿学]