饮用水中全氟化合物暴露对妊娠结局的影响调查  

Investigation on the effect of exposure to perfluorinated compounds in drinking water on pregnancy outcome

作　　者：孙林[1] 邓冰[1] 张琦豪[1] 范霞林 王加好[1] 

机构地区：[1]贵阳医学院医学心理学教研室,贵州贵阳550004

出　　处：《中国妇幼保健》2015年第10期1577-1578,共2页Maternal and Child Health Care of China

基　　金：国家自然科学基金项目〔81260429〕;贵州省科技厅攻关项目〔黔科合SY字(2012)3128号〕

摘　　要：目的：了解孕产妇经饮用水接触全氟化合物与不良妊娠结局之间的相关性,为生殖健康及妇幼保健工作提供参考。方法：采用问卷调查的方法,选取2013年1月-11月在贵阳市某医院产前诊断中心进行产检的孕产妇,了解其在孕期经饮用水接触全氟化合物的相关信息以及妊娠结局情况。结果：饮用管道自来水与不饮用管道自来水的孕产妇不良妊娠结局比较差异有统计学意义（P〈0.05）,而饮用净化自来水、瓶装水及桶装水与不饮用净化自来水、瓶装水及桶装水的孕产妇不良妊娠结局比较差异无统计学意义（P〉0.05）。结论：为了降低不良妊娠结局的发生率,孕期女性应注重饮用水安全,同时相关部门应加大食品安全管理,重视PFCs的危险性,尽可能地避免接触全氟化合物。Objective： To understand the correlation between exposure to perfluorinated compounds through drinking water and ad- verse pregnancy outcome of pregnant women, provide reference for reproductive health and maternal and child health care. Methods： A questionnaire survey was performed, the pregnant women receiving prenatal examination in Prenatal Diagnosis Center of a hospital in Guiyang city were selected, the related information about exposure to perfluorinated compounds through drinking water during pregnancy and pregnan- cy outcome was collected. Results： There was statistically significant difference in maternal adverse pregnancy outcome between the pregnant women drinking tap water and the pregnant women not drinking tap water （P 〈 0. 05 ） ; there was no statistically significant difference in ma- ternal adverse pregnancy outcome between the pregnant women drinking purified water, bottled water, and barrelled water and the pregnant women not drinking purified water, bottled water, and barrelled water （ P 〉 0. 05） . Conclusion： In order to reduce the incidence rate of adverse pregnancy outcome, pregnant women should pay attention to safety of drinking water, while the relevant departments should strengthen food safety management, pay attention to the risk of perfluorinated compounds, and avoid contact with perfluorinated compounds as much as possible.

关 键 词：全氟化合物 饮用水 不良妊娠结局 危险因素 

分 类 号：R715.9[医药卫生—妇产科学]