复合声治疗突发性聋患者耳鸣的临床对照研究  

The clinical efficacy of composite acoustic therapy in patients of sudden deafness with tinnitus

作　　者：刘钊[1] 梁勇[1] 杨衬[1] 刘友利[1] 李衍菲[1] 韩晓燕[1] 曾林燕[1] 何萍香 

机构地区：[1]南方医科大学南方医院耳鼻咽喉头颈外科,广州510515

出　　处：《临床耳鼻咽喉头颈外科杂志》2015年第4期330-333,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的：观察复合声治疗突发性聋患者耳鸣的临床疗效,并探讨作用机制。方法：将96例（96耳）突发性聋伴耳鸣患者分为试验组和对照组,进行14d的药物治疗,试验组前30天加入个性化复合声治疗,31~90d改音乐治疗,对照组不加声治疗。在治疗前、第30天、第90天对两组患者进行纯音测听、耳鸣匹配、残余抑制等听力学检查,填写耳鸣响度VAS量表、THI量表、SAS量表,比较结果。结果：89例（试验组47例、对照组42例）完成本试验。两组第30天比较：VAS评分、听力恢复率差异均无统计学意义（P〉0.05）,THI评分、SAS评分差异均有统计学意义（P〈0.01）。第90天比较：VAS评分、THI评分、SAS评分差异均有统计学意义（P〈0.05或P〈0.01）,听力恢复率差异无统计学意义（P〉0.05）。两组VAS评分有显著差异出现在治疗前30天。两组听力恢复率、试验组耳鸣VAS评分,前30天疗效好于31~90d（P〈0.01）。结论：复合声联合药物治疗可以改善突发性聋患者的耳鸣和焦虑,其对耳聋的疗效仍有待观察。Objective：To determine whether the composite acoustic therapy is effective to treat tinnitus in patients with sudden deafness and to explore the mechanisms.Method：Ninety-six cases（96ears）were divided into experimental group and control group,and all the patients underwent drug treatment.The patients in experimental group were given personalized composite acoustic therapy in the first 30 days,music therapy in next 31-90 days,however,the patients in control group were not given sound therapy.Additionally,pure tone audiogram,tinnitus pitch and loudness as well as questionnaires（including THI,VAS,and SAS）were conducted for each patient before treatment,at day 30 and day 90 posttreatment.Result：Eighty-nine patients（n=47for experimental group and n=42for control group）completed the trial.The results of day 30 posttreatment showed there were no significant differences in VAS and hearing recovery rate between these two groups,but THI and SAS showed significant differences.The results of day 90 posttreatment showed significant differences in VAS（P〈0.05）,THI（P〈0.01）and SAS（P〈0.01）,and no significant difference of hearing recovery rate was detected.The most significant changes of VAS appeared in the first 30 days of treatment.The hearing and tinnitus recovery in experimental group were better for the first 30 days of treatment than for the next 31-90 days,and similar results were obtaind in control group.（P〈0.01）.Conclusion：Composite acoustic treatment combined with drug therapy can improve the tinnitus and anxiety symptoms of patients with sudden deafness,and the effect on hearing recovery still need to be confirmed in further studies.

关 键 词：复合声 听觉丧失 突发性 耳鸣 焦虑 

分 类 号：R764.45[医药卫生—耳鼻咽喉科]