ANCA相关性血管炎3例  

Three Cases of ANCA Associated Vasculitis

作　　者：陈叶青[1] 周国华[1] 王珍香[1] 周红宇[1] 刘明亮[1] 

机构地区：[1]解放军第一六九医院暨湖南师范大学附属湘南医院消化内科,湖南衡阳421002

出　　处：《中国皮肤性病学杂志》2015年第3期296-298,317,共4页The Chinese Journal of Dermatovenereology

摘　　要：抗中性粒细胞胞浆抗体相关性血管炎是比较少见的疾病,临床表现不典型,易漏诊。该文分析3例抗中性粒细胞胞浆抗体相关性血管炎的诊治经过,患者均有纳差、乏力、肺部感染、肾功能损害,本病易合并其他结缔组织疾病。抗中性粒细胞胞浆抗体(ANCA)常阳性,c ANCA合并抗PR3抗体阳性或p ANC合并抗MPO抗体阳性用于诊断本病特异性可达99%。临床上应结合病史、血沉、C反应蛋白、抗核抗体谱、抗ENA抗体谱、血管炎四项等检查综合分析,以提高诊断率。ANCA associated vasculitis （ AASV） is a rare disease with atypical clinical manifestation that can be easyly missed diagnosis. Through the analysis of the diagnosis and treatment of three AASV ,we found that all pa- tients had poor appetite, fatigue, pulmonary infection and impairment of renal function. AASV is easily com- bined with other desmosis. Antineutrophil cytoplasmic antibody is usually positive, cANCA and PR3 or pANC and MPO antibody positive can diagnose AASV withthe specificity of 99%. We should combine the comprehensive analyses of history, ESR, C reactive protein, Antinuclear antibody, anti ENA antibodies, and vasculitis four assays to improve the diagnostic rate.

关 键 词：抗中性粒细胞胞浆抗体相关性血管炎 诊断 治疗 

分 类 号：R543[医药卫生—心血管疾病]