心电标测系统中激动时刻提取方法的比较研究  

Comparative research on extracting methods of activation time in cardiac mapping system

作　　者：王彦磊[1] 杨翠微[1,2] 余建国[1] 

机构地区：[1]复旦大学电子工程系,上海200433 [2]上海市医学图像处理与计算机辅助手术重点实验室,上海200433

出　　处：《仪器仪表学报》2015年第3期661-667,共7页Chinese Journal of Scientific Instrument

基　　金：国家自然科学基金(61071004);上海市自然科学基金(15ZR1403400)资助项目

摘　　要：心电标测系统中除极波的激动时刻判定是一个非常重要的工作,但目前针对单极和双极信号的激动时刻提取方法还没有形成共识。本文总结和实现了现有的几种激动时刻提取算法,提出一种符合单双极信号生理意义的检验激动时刻提取准确性的判断标准,比较了5种算法分别应用于单极和双极信号时的提取效果,并通过实际的动物实验数据进行了验证。统计结果表明,单极信号的激动时刻提取应采用考虑到心电信号电生理意义的负向最大斜率法和空间梯度法;而双极信号的激动时刻提取更适合从信号波形形态学出发,可采用最大峰值法、负向最大斜率法和局部重心法3种方法。Designation of the activation time of the depolarization wave is significant to cardiac mapping system,yet there isn＇t any consensus on the methods of extracting activation time for unipolar and bipolar signals.The article implements several existing methods and proposes evaluation criteria based on the electrophysiological significance of these two kinds of signals to judge the veracity of the methods.We compare the effects of these five methods on unipolar and bipolar signals of animal experimental data.Statistical results show that methods the maximum slop method and the spatial gradient method are appropriate for unipolar signals due to their electrophysiological significance;while morphology-based methods the maximumpeak the maximum slop method and the local barycenter method should be applied to bipolar signals.

关 键 词：心电标测 激动时刻 单极 双极 电生理 

分 类 号：TH789[机械工程—仪器科学与技术] R318.6[机械工程—精密仪器及机械]