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作 者:杨彩琴[1] 王旭梅[2] 公洁[1] 尹国栋[1]
机构地区:[1]张掖市人民医院耳鼻咽喉科,甘肃张掖734000 [2]肃南县人民医院检验科,甘肃张掖734400
出 处:《中国医学文摘(耳鼻咽喉科学)》2015年第1期41-42,共2页Chinese Medical Digest(Otorhinolaryngology)
摘 要:目的探讨153例外耳及中耳感染患者病原菌种类分布及药敏情况,指导临床用药。方法收集2012年10月15~2014年4月15我院门诊就诊的耳道流液患者153例,采用K-B法进行病原菌药敏试验。结果外耳道和中耳感染患者病原菌比例为葡萄球菌占44.44%,铜绿假单胞菌6.45%,真菌30.07%,无细菌生长8.50%。敏感药物因菌种而宜。药敏试验对临床合理用药有指导意义。结论耳部常见感染菌以G+菌多见,真菌次之,G﹣菌第三。药敏结果分析G+对头孢唑林、头孢西丁、左氧氟沙星敏感,G﹣对头孢哌酮舒巴坦、头孢他啶敏感。MRS仅对左氧氟沙星敏感。红霉素、克林霉素耐药率高。在目前合理应用抗菌素的大背景下,对各位临床同仁在治疗外中耳感染患者时,最有效的选用抗生素和针对性治疗提供帮助。Objective To explore the bacterial spectrum and drug sensitivity of pathogen of ear bacterial infections and toguidethe clinical treatment. Methods Samples of 153 patients with ear infection from October 15 2012 to April 15 2014 in the Zhangye people' s hospital were collected by routine method, and K-B method was used for drug susceptibility test. Results The ear pathogenic bacteria were isolated. The main pathogenic bacteria were staphylococcus aureus, accounting for 44.44%, pseudomonas aeruginosa of 6.45%, fungus of 30.07%, no bacteria of 8.50%. Drug sensitivity varied according to the bacterial species. Drug sensitivity test can guide clinical drug prescription. Conclusions The most common pathogens of ear bacterial infections are G+ bacteria, then Fungus, and G-negative (G-) bacteria are the third. G+ bacteria were sensitive to cefazolin, cefoxitin, levofloxacin. MRS were only sensitive to levofloxacin, and G- bacteria were sensitive to cefoperazone sulbactam, ceftazidime. Resistance to Erythromycin and elindamycin is high. The study is helpful for the use of antibiotics and targeted therapies.
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