硫酸镁对胆总管取石术后患者胆道压力和胆汁分泌的影响  

Effect of magnesium sulfate on biliary pressure and bile secretion in patients after choledocholithotomy

作　　者：陈兆永[1] 王凯[1] 范育珠 刘宜翔[1] 李强[1] 朱洪波[1] 

机构地区：[1]连云港市东方医院普通外科,江苏省222042

出　　处：《江苏医药》2015年第4期442-443,共2页Jiangsu Medical Journal

摘　　要：目的探讨硫酸镁对胆总管取石术后患者胆道压力和胆汁分泌的影响。方法行胆总管切开取石术后T管引流患者20例均分为两组:实验组予25%硫酸镁10ml+生理盐水250ml静脉滴注,每天1次,治疗8d;对照组仅予生理盐水250ml静脉滴注。治疗期间,每天利用T管测定胆道压力,记录24-h胆汁引流量。结果术后第4-8天,实验组静脉输液后胆道压力低于对照组(P<0.05),且24-h胆汁引流量少于对照组(P<0.05)。结论胆总管取石术患者术后静脉应用硫酸镁可降低胆管压力,减少胆汁引流量。Objective To explore the effect of magnesium sulfate on biliary pressure and bile secretion in the patients after choledocholithotomy.Methods Twenty patients underwent choledocholithotomy and T-tube drainage were equally divided into two groups.The patients in group A after operation were infused 25% magnesium sulfate 10 ml in normal saline 250 ml daily for continuous 8days and those in group B were given normal saline 250 ml as the controls.The biliary pressure was measured via T-tube and 24-h bile drainage was recorded once a day during treatment.Results The biliary pressure after intravenous flouid infusin on the 4th to 8th day after operation was lower in group A than that in group B（P〈0.05）.The 24-h drainage amount of bile was less in group A than that in group B（P〈0.05）.Conclusion Intravenous infusion of magnesium sulfate can reduce the biliary pressure and 24-h drainage amount of bile in the patients after choledocholithotomy.

关 键 词：硫酸镁 胆总管取石术 

分 类 号：R657[医药卫生—外科学]