入院Hcy水平对急性ST段抬高心肌梗死患者预后的影响  

Effect of Admission Hcy Level on the Prognosis of Patients with Acute ST Segment Elevation Myocardial Infarction

作　　者：杨平[1] 

机构地区：[1]辽宁中医药大学附属医院干诊科,辽宁沈阳110032

出　　处：《标记免疫分析与临床》2015年第3期190-192,共3页Labeled Immunoassays and Clinical Medicine

摘　　要：目的观察入院为急性ST段抬高心肌梗死患者,血Hcy水平对患者预后的影响。方法入选60例急性ST段抬高心肌梗死患者(均为行冠脉造影证实为单支血管急性血栓),根据入院Hcy水平分为高Hcy组(Hcy≥10μmol/L)33例和正常Hcy组(Hcy<10μmol/L)27例,观察并比较两组患者基线水平特征,分析院内的病死率和主要不良心血管事件(MACE)发生率。结果单因素变量分析显示,两组患者在BNP,血压指标上的基线水平差异具有统计学意义(P<0.05);高Hcy组住院期间病死率和不良心血管事件发生率较正常Hcy组明显升高,差异有统计学意义(P<0.05)。结论对于急性ST段抬高心肌梗死患者,高Hcy水平患者预后较Hcy正常者差,Hcy水平可能是急性心肌梗死预后的一个独立预测指标。Objective To investigate the effect of blood Hcy level on the prognosis of patients with acute ST segment elevation myocardial infarction. Methods 60 patients with acute ST segment elevation myocardial infarction which confirmed by coronary angiography single vascular acute thrombosis were divided into high Hcy group（ Hcy ≥ 10μmol / L,33 cases） and normal Hcy group（ Hcy 10μmol / L,27 cases） according the Hcy level. Two groups of patients were observed and compared baseline characteristics,and in- hospital mortality and major adverse cardiac events（ MACE） rate. Results There were significantly different on baseline levels of BNP and blood pressure between two groups（ P〈0. 05）. High Hcy group in- hospital mortality and incidence of adverse cardiac events was significantly higher than normal Hcy group（ P〈0. 05）. Conclusion For patients with acute ST segment elevation myocardial infarction（ mi）,the prognosis of patients with high Hcy levels is worse than normal Hcy. The levels of plasma Hcy may be an independent prediction index of prognosis in patients with acute myocardial infarction.

关 键 词：同型半胱氨酸 急性ST段抬高心肌梗死 预后 

分 类 号：R542.22[医药卫生—心血管疾病]