全容积心脏成像技术评价二参通脉颗粒对气虚血瘀证心肌梗死的疗效  

Evaluation of Ershentongmai granules′ effection on acute myocardial infarction patients with qi deficiency and blood stasis syndrome by full-volume three-dimensional echocardiography

作　　者：张楠[1] 司国民[2] 李巧[1] 杨明[1] 牟慧珺[1] 郭振伟 

机构地区：[1]山东大学附属省立医院超声诊疗科,山东济南250021 [2]山东大学附属省立医院

出　　处：《社区医学杂志》2015年第5期42-44,共3页Journal Of Community Medicine

摘　　要：目的采用全容积心脏成像技术评价二参通脉颗粒对气虚血瘀证心肌梗死的疗效。方法选择2012年1月—2014年1月收治的气虚血瘀证心肌梗死患者60例作为研究对象,随机分为对照组和观察组各30例。对照组接受常规治疗,观察组在对照组基础上加用二参通脉颗粒。应用全容积心脏成像技术观察患者治疗前后超声心动图相关指标的变化。计量资料组间比较采用t检验,组内比较采用配对t检验,P<0.05为差异有统计学意义。结果观察组治疗前左室舒张末期容量(left ventricular end-diastolic volume,LVEDV)、左室收缩末期容量(left ventricular end-systolic volume,LVESV)、每搏量(stroke volume,SV)、心输出量(cardiac output,CO)、左室射血分数(left ventricular ejection fraction,LVEF)分别为(166.10±9.60)、(94.37±10.26)、(71.73±11.94)ml、(5.97±0.87)L/min、(43.10±6.06)%,治疗后分别为(159.20±9.80)、(80.43±9.59)、(78.77±11.77)ml、(6.44±1.03)L/min、(49.40±5.87)%;对照组治疗前分别为(158.80±11.86)、(89.44±13.59)、(69.36±5.82)ml、(5.81±0.69)L/min、(43.90±4.93)%,治疗后分别为(151.20±10.49)、(69.96±8.60)、(81.23±6.70)ml、(6.68±0.97)L/min、(53.80±3.74)%。两组以上各指标治疗前后差异均有统计学意义,且治疗后两组LVEDV、LVESV、LVEF差异均有统计学意义(均P<0.05)。结论二参通脉颗粒对气虚血瘀证心肌梗死有显著疗效,全容积心脏成像技术可作为疗效评价的重要观察指标。Objective To evaluate the effection of Ershentongmai granules on acute myocardial infarction patients with qi deficiency and blood stasis syndrome by full-volume three-dimensional echocardiography.Methods Sixty cases of qi deficiency and blood stasis syndrome with acute myocardial infarction from January 2012 to January 2014 were chosen and dividedjandomly into two groups：the observation group and the control group.Patients in the control group were treated with routine medicine and those in the observation group were treated additionally by Ershentongmai granules.Full-volume three-dimensional echocardiography was performed to evaluate the changes of heart structure and functions before and after the treatment in both groups.Comparison of measurement data between groups using t-test, in group were compared with paired .t-test.There were statistically significant differences in P〈0.05.Results The left ventricular end-diastolic volume （LVEDV）,left ventricular end-systolic volume（LVESV）, stroke volume（SV）,cardiac output（CO） and left ventricular ejection fraction（LVEF） were （166.10 ± 9.60）,（94.37 ± 10.26）,（71.73 ± 11.94）ml,（5.97 ± 0.87）L/rain and （43.10 ± 6.06）% in observation group before treatment,（159.20 ± 9.80）,（80.43 ± 9.59）,（78.77 ± 11.77）ml,（6.44 ± 1.03）L/min,（49.40 ± 5.87）% after treatment;and （158.80 ± 11.86）,（89.44 ± 13.59）,（69.36 ± 5.82）m1,（5.81 ± 0.69） L/min, （43.90 ± 4.93）% in control group before treatment, （151.20 ± 10.49）, （69.96 ± 8.60）, （81.23 ± 6.70）ml, （6.68 ± 0.97）L/rain,（53.80 ± 3.74）%after treatment.All indicators before and after treatment similar between the two groups have statistical significance,and the LVEDV,LVESV,LVEF of the two group after treatment have statistical significance（all P〈0.05）.Conelusion Ershentongmai granules can improve the cardiac functions of acute myocardial infarction patients with qi deficiency and blood stasis syndrome.Full-volume three-

关 键 词：全容积心脏成像技术 气虚血瘀证 心肌梗死 二参通脉颗粒 左室射血分数 

分 类 号：R256.22[医药卫生—中医内科学]