侵华日军鼠疫细菌战幸存者F1抗体血清调查  

Investigation of plague F1 antibody level in serum of survivors suffered from bacterial warfare during anti Japanese war

作　　者：陈秀英[1] 雷永良[1] 庄启俭 柳付明[1] 丛迎[1] 梅建华[1] 

机构地区：[1]浙江省丽水市疾病预防控制中心,浙江丽水323000 [2]丽水市档案局,浙江丽水323000

出　　处：《疾病监测》2015年第1期38-41,共4页Disease Surveillance

摘　　要：目的通过对日军鼠疫细菌战幸存者流行病学资料调查和F1抗体检测分析,为浙江省丽水市历史上鼠疫暴发是日军细菌战所引发提供生物学证据。方法通过浙西南"侵华日军细菌战"档案抢救与保护中心寻访到丽水市36名鼠疫细菌战受害幸存者,采用回顾性个案调查的方法进行流行病学调查,并采集静脉血标本进行鼠疫F1抗体检测。结果时隔70年,仍能从当年国民政府诊断为鼠疫患者的25%的幸存者中检测到高滴度F1抗体。结论日军细菌战制造了一个严重的细菌污染区,留下长期隐患,给丽水市当地居民带来了巨大的伤害。Objective To provide biological evidence to confirm that the plague outbreaks in the history of Lishui were caused by Japanese bacterial warfare through analyzing the epidemiological data and detection of F1 antibody of the survivors. Methods Thirty six plague survivors of Japanese bacterial warfare were found by retrieving archive records. Retrospective epidemiological survey was conducted among the survivors and blood samples were taken from them to detect plague F1 antibody. Results More than 70 years later, high titer F1 antibody could be still detected from 25 % of the diagnosed plague survivors. Conclusion A severely contaminated area was left behind in Lishui after Japanese bacterial warfare, which posed serious potential health risk for local people for a long period.

关 键 词：幸存者 细菌战 F1抗体 

分 类 号：R516.8[医药卫生—内科学]