气相色谱法同时测定制药企业废气中多种挥发性有机物  

Simultaneous Determination of Multiple VOCs in Waste Gas of Pharmaceutical Industry by Gas Chromatography

作　　者：冯媛[1] 吕溪[2] 姜建彪 宋玉[2] 任爱玲[2] 杨丽丽[1] 

机构地区：[1]石家庄市环境监测中心,河北石家庄050022 [2]河北科技大学环境科学与工程学院,河北石家庄050018

出　　处：《中国环境监测》2015年第1期104-108,共5页Environmental Monitoring in China

基　　金：环境保护公益性行业科研专项"制药行业VOCs与恶臭控制技术政策研究"(201109004)

摘　　要：针对典型制药产品青霉素、阿莫西林、维生素C、对乙酰氨基酚生产过程的挥发性有机物（VOCs）排放特点,建立了吸附-解吸-气相色谱法同时检测制药企业废气中丙酮、乙酸乙酯、异丙醇、苯、甲苯、乙酸丁酯和正丁醇等7种特征VOCs的分析方法.采用活性炭采样管采样-二硫化碳解吸-毛细管色谱柱分离,在解吸时间30 min、柱温35℃保持6 min、30℃/min速率升温到200℃保持2 min的色谱分析条件下,各挥发性有机物可以实现良好的分离;7种物质标准曲线相关系数为0.999 8-0.9999,相对标准偏差为1.1％ -3.2％,检出限为0.004 mg/m3 -0.014 mg/m3,7种物质的解吸效率为83.1％-105.1％.结果表明,该方法适用于典型制药企业固定污染源排放废气中特征VOCs的测定.Directing at emission characteristics of VOCs in the production process of typical pharmaceutical products such aspenicillin, amoxicillin, vitamin C and 4-acetamidophenol, the analytical method for simultaneous determination of sevencharacteristic VOCs as acetone, ethyl acetate, isopropyl alcohol, benzene, toluene, ethyl acetate and n-butanol in waste gas ofpharmaceutical industry by adsorption-desorption-GC method was established. Using activated charcoal adsorption to sample-carbon disulfide to desorb-capillary chromatographic column to separate, under the analytical conditions of maintaining the columntemperature at 35 ℃ for 6 minutes and raising the temperature at the rate of 30 ℃ per minute to 200 ℃ and maintaining for 2minutes, each volatile organic compounds can actualize good separation; the correlation coefficients of the calibration curve werefrom 0. 999 8 to 0. 999 9, relative standard deviations were from 1. 1% to 3.2% , and detection limits were from 0. 004 mg/m3 to0. 014 mg/m3 , and the desorption efficiency of seven compounds were from 83. 1% to 105.1%. The result demonstrated that themethod was suitable for the determination of VOCs of the stationary source emission of typical pharmaceutical industry.

关 键 词：气相色谱法 制药企业废气 挥发性有机物 吸附 解吸 

分 类 号：X830.2[环境科学与工程—环境工程]